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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Novel Polymeric Trileaflet Heart Valve Prosthesis

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The development of a durable, hemocompatible valve prosthesis is the long-term objective of this proposal. While heart valve prostheses have been used successfully since 1960, 10-year survival rates still range from

    SBIR Phase I 2004 Department of Health and Human Services
  2. Fail-safe TET system for implanted life support devices

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cardiac assist devices are increasingly being used for long term support. As patient survival times increase substantially, long-term management of the patients will increasingly play a role in suitability of these

    SBIR Phase I 2004 Department of Health and Human Services
  3. A Smart Polymer for Destination Cardiac Assist Devices

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cardiac assist devices are increasingly being used for long term support. As patient survival times increase substantially, device wear-out will increasingly play a role in the clinical management of patients with l

    SBIR Phase I 2004 Department of Health and Human Services
  4. Targeted Prodrug Therapy of Liver Cancers

    SBC: ACCLAIM BIOTECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) and colorectal cancer (CRC) are among the most common and deadly malignancy worldwide. CRC is the second leading cause of cancer-related death in the USA, mostly due to metastases to the

    SBIR Phase I 2004 Department of Health and Human Services
  5. Three Dimensional ECM Scaffolds for Tissue Engineering

    SBC: ACELL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I SBIR application seeks support to develop a three dimensional acellular scaffold composed of particulate extracellular matrix (ECM). Products composed of the two dimensional (sheet form) of ECM der

    SBIR Phase I 2004 Department of Health and Human Services
  6. Rare Cell Isolation for Morphological & Molecular Study

    SBC: Adeptas, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A first step in the elucidation of the genetic changes and molecular profiles associated with the development of cancer is the isolation of rare tumor cells from a background of millions of normal cells, or the fracti

    SBIR Phase I 2004 Department of Health and Human Services
  7. New Agents That Inhibit Fatty Acid Accumulation

    SBC: ADIPOGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Existing treatments for obesity are only modestly effective. The mission of AdipoGenix, Inc. is

    SBIR Phase II 2004 Department of Health and Human Services
  8. Automated Detection of Gene Duplications or Deletions

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This project will further develop automated instrumentation and image analysis techniques to detect gene duplications or deletions in interphase FISH, which are difficult to detect by routine cytogenetics. There is a

    SBIR Phase II 2004 Department of Health and Human Services
  9. Multiresolution Autofocusing for Automated Microscopy

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This project will further develop and refine an innovative digital auto-focus technology for automated microscopy. Auto-focusing is essential to automated microscope imaging. Currently available techniques rely on v

    SBIR Phase II 2004 Department of Health and Human Services
  10. Lossless ROI Watermarking of Medical Images

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop innovative lossless regions-of-interest (ROI) watermarking techniques to make the usage, archiving, and communication of medical images much more secure and manageable. Currently

    SBIR Phase I 2004 Department of Health and Human Services

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