Award Data

Collaboration-Optimized Network for Naturalistic Exploration and Communication about Traffic (CONNECT) 3/19/2018 Collaboration-Optimized Network for Naturalistic Exploration and Communication about Traffic (CONNECT) will be a tool that allows users to easily generate a wide range of data visualizations from the Fatality Analysis Reporting System (FARS). CONNECT will leverage open-source visual ...

Proposal title: Detection of THC Use in Drivers The overall objective of this program is to develop a portable, cost-effective and non-invasive sensor device for near real-time salivary THC detection to be used at roadside in drivers. This will eliminate the need for expensive and time-consuming analytical techniques which have a turn-around time of several days. During the Phase I program Giner ...

Proposal title: A Robust Railway Track Crack Detection System Using Thermal Signatures In Phase I, we developed a practical sensor platform suitable for mounting on the back of train. A large amount of IR images associated with rail tracks were collected on an MBTA train. Algorithms were developed to identify both right and left tracks from a moving train. To help detect track cracks, we develope ...

Proposal title: Detection of THC Use in Drivers The intoxicating effects of marijuana are of concern to the law enforcement community as well as to the general manufacturing, service and commerce community where employees may need to be screened for intoxication. A reliable method to quantitatively measure the amount of the intoxicating agent delta-9- tetrahydrocannabinol (THC) in suspected marij ...

This project develops an ultrasonic fitment tool to improve prosthetics performance for persons with lower-extremity amputations. The goal of this project is to develop a new clinical instrument used in the socket fitting process to optimize the performance of a lower-body prosthetic system and thereby improve mobility, activity, exercise, and quality of life for over 2 million American amputees. ...

This proposal addresses the significant public health threat posed by the spread of Taenia soliumthe pork tapewormin at risk human populationsInfection with Tsoliumor Taeniasiscan lead to Cysticercosiscaused by the migration and encystment of larval Tsolium in the central nervous systemCysticercosis is a severe to fatal disease which affects overmillion people worldwideprincipally in less develope ...

Fungal endophthalmitis is an infection inside the eye after corneal transplant surgery caused by contamination of the transplanted tissueAccording to the Eye Bank of Americathe incidence of postsurgery endophthalmitis more than doubled fromtoand thatof the culture positive cases were due to Candida yeastEnvironmental contamination as well as current corneal preservation conditions contribute to th ...

Cancer patients receiving radiation therapy experience toxic side effects of the radiation, and sensitivity to radiation is variable across both patients and tumors, and is poorly understood. This Phase I SBIR project aims to design and demonstrate the feasibility of a Patient Reported Outcome mobile application for surveillance of RADiotherapy toxicity (PRORAD) that integrates NIH's Patient Repor ...

Here we propose to study two injectable formulations that provide different delivery routes for Talazoparib, potent PAPR inhibitor: An implant, InCeT-Talazoparib, which can be injected directly in the tumor where it will act as a sustained release depot of Talazoparib over a prolonged period of approximately 30 days. It delivers 100% of the drug to the tumor site with almost no systemic toxicity. ...

Cancer survivors commonly report cognitive impairments following chemotherapy. With a growing number of cancer survivors comes an increased urgency to better understand the precise etiology and prevalence of cognitive changes associated with cancer and cancer treatment. This pursuit is impeded by a lack of assessment tools that can accurately detect the full scope of cognitive deficits. To address ...