Award Data

This project develops an ultrasonic fitment tool to improve prosthetics performance for persons with lower-extremity amputations. The goal of this project is to develop a new clinical instrument used in the socket fitting process to optimize the performance of a lower-body prosthetic system and thereby improve mobility, activity, exercise, and quality of life for over 2 million American amputees. ...

Cancer survivors commonly report cognitive impairments following chemotherapy. With a growing number of cancer survivors comes an increased urgency to better understand the precise etiology and prevalence of cognitive changes associated with cancer and cancer treatment. This pursuit is impeded by a lack of assessment tools that can accurately detect the full scope of cognitive deficits. To address ...

PROJECT SUMMARY In response to the growing need for training on interventions to address first episode psychosis, the Center for Social Innovation (C4) has partnered with experts in Coordinated Specialty Care (CSC) to develop and test CSC OnDemand: An Innovative Online Learning Platform for Implementing Coordinated Specialty Care. The product builds on the findings of the Recovery After an Initial ...

PROJECT SUMMARYStroke is a major public health problem in the U Sand worldwideIt is defined as an area of brain damagegenerally due to the sudden occlusion of an artery in or leading to the brainStroke can cause weaknessnumbnessvisual disturbancespeech difficultybalance problemsand memory lossamong other symptomsWhile good treatments exist to limit stroke in the first few hours after occurrencefew ...

Project Summary AbstractThe goal of the proposed SBIR program is to develop a pharmaceutical manufacturing decontamination system using the innovative PSI atmospheric pressure microwave microplasma technologyCommercialization of this technology is targeted to replace the use of vapor phase hydrogen peroxideVPHPin parenteral drug manufacturing facilitiesincluding barrier isolator sterilization syst ...

The CDC reports that food allergy incidence in the U Sis risingwithof children now afflicted andhaving a history of severe and potentially life threatening reactionsIn order to reduce this high incidencenew guidelines recently issued by the NIAID and also by leading allergists recommend that children betweenmonths of age be introduced to highly allergenic foods such as peanutsmilk and eggsIn addit ...

Project Summary Abstract This Phase II project aims to develop an automated system for extracting mesenchymal stem cellsMSCsalso known as multipotent stromal cellsfrom adipose tissues for treating many serious diseasesincluding myocardial infarctiongraft versus host diseaseand a variety of autoimmune diseasesOverclinical trials to date have established the feasibilitysafetyand in some cases effica ...

Systemic lupus erythematosusSLEis a complex autoimmune disease with a broad spectrum of clinical manifestations that affect several organsSLE affects millions of individualswith women and minorities disproportionately burdenedand is associated with significant morbidity and mortalityDespite considerable progress made towards understanding the disease and the identification of the central roles pla ...

ABSTRACT Next generation sequencingNGShas the potential to revolutionize how infectious disease is diagnosed and treatedenabling the detection of a wide variety of pathogens in a single testHoweverdespite the increasing adoption of molecular diagnostics in clinical microbiology labsNGS has not become widespread due to its costturnaround timeand the technical and computational expertise required to ...

Project Summary Abstract Physical Sciences IncPSIis continuing the pursuit of new clinical applications and advanced multimodal capabilities for its novel retinal imaging technology based on an adaptive optics line scanning ophthalmoscopeAO LSOThe Compact Adaptive Optics Retinal ImagerCAORIeliminates high speed scanning componentsreduces the clinical footprint compared to research adaptive optics ...