List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Cost efficient optical guidance for spinal fusion using existing radiographic equipment and augmented reality display

    SBC: OnPoint Spine, Inc.            Topic: NIBIB

    ABSTRACT The technology that will be developed in this NIH SBIR Phase I and later Phase II proposal will provide novel systems for optical guidance of spinal surgery that will not use any of the expensive components currently used for surgical navigation intra operative CT or O arm imaging or robotics Instead the technology will leverage innovative new hardware such as optical head mounted d ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Novel D Printed Architectures for Oral Long acting Drug Delivery Systems

    SBC: Lyndra Therapeutics, Inc.            Topic: NIBIB

    Novel D Printed Architectures for Oral Long Acting Drug Delivery Systems Project Summary Long acting oral LAO dosage forms may offer significant benefits for managing chronic medical conditions requiring long term and intensive medication regimens particularly those in which observed therapy would be practical and advantageous such as psychiatric disorders Poor patient adherence and persist ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Drug eluting Brachytherapy Implants for Chemo radiation Therapy

    SBC: TheraNano LLC            Topic: 102

    Prostate cancer PCa is the second leading cause of cancer death in American men with deaths and new cases estimated in the US in Radiation therapy is one of the standard therapies for high and intermediate risk patients and is a non surgical therapy option for low risk patients A combined chemo radiation therapy CRT approach has been shown in several trials to improve s ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Management of bioburden and tissue regeneration in diabetic wounds using engineered matrices

    SBC: GEL4MED, INC.            Topic: 300

    The goal of this Phase I SBIR proposal is to demonstrate the feasibility of an inherently broad spectrum antimicrobial tissue scaffolding matrix capable of eliminating infecting bacterial pathogens and improve wound closure in diabetics Delayed non healing diabetic wound is responsible for about annual non traumatic lower limb amputations in the US Microbial infections further complica ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. First in class TREM inhibitors in combination therapy for pancreatic cancer

    SBC: SIGNABLOK, INC.            Topic: 102

    Project Summary Abstract Carcinoma of the pancreas or pancreatic cancer PC is the fourth leading cause of cancer related death in the United States According to the American Cancer Society new cases are expected in Despite advances in therapy the year survival rate is less than Current treatments of PC include surgery radiation therapy chemotherapy and immunotherapy bu ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. High channel count electrophysiology and data processing for freely moving animals

    SBC: Leaflabs, LLC            Topic: 101

    PROJECT SUMMARY Simultaneous recording and stimulation of larger populations of neurons distributed throughout the brain is needed to rigorously evaluate theories of neural computation at the cellular level in mammals Previously we introduced close packed silicon probes Scholvin et al and a direct to disk data acquisition architecture Kinney et al to enable channel neural ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Structure Based Potential for Protein Mapping

    SBC: ACPHARIS            Topic: 100

    The binding sites of proteins include smaller regions called hot spots that are major contributors to the binding free energy and hence are crucial to binding any ligand at that site Hot spots can be determined by screening libraries of fragment sized organic molecules for binding to the target protein by X ray crystallography or nuclear magnetic resonance NMR The computational mapping algori ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Handheld Two Photon Microscopy Imager

    SBC: Physical Sciences Inc.            Topic: 102

    Project Summary Abstract Physical Sciences Inc PSI proposes to develop a handheld two photon microscopy TPM probe that will enable in vivo diagnosis and screening of various diseases including cancers This novel clinically usable TPM instrument will provide three dimensional D sub micron resolution images of tissue pathology in situ The images generated based on the two photon excitat ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Development of TP for the Induction and Maintenance of Remission in Ulcerative Colitis Patients

    SBC: Thetis Pharmaceuticals LLC            Topic: 300

    ABSTRACT Thetis plans to investigate TP an innovative and potential first in class therapeutic agent as an oral therapy for the induction and maintenance of remission of intestinal inflammation symptoms in ulcerative colitis UC patients While the precise etiology of UC is unknown it is thought to result from an inappropriate inflammatory response to commensal gut bacteria in genetically ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Neuro Optical Diagnostic System for Macular Degeneration

    SBC: NEUROFIELDZ INC.            Topic: NIA

    Age related macular degeneration AMD causes progressive loss of central vision and is the leading cause of blindness in the developed world A major challenge in the development of effective treatments for AMD is the lack of sensitive practical visual function endpoints People with AMD manifest delayed dark adaptation DA recovery and DA tests are a FDA approved method for diagnosing AMD Cu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government