Award Data

DESCRIPTION (provided by applicant): The objective of this proposed program is to develop a general purpose anastomotic device for large vessels and vascular grafts, based on a novel stapler design. The use of the device can provide an alternative procedure to the current manual suturing methods, with the potential of yielding anastomoses having better and more reproducible performance, and with r ...

DESCRIPTION (provided by applicant): The overall objective of this proposed program is the commercialization of an advanced intraventricular cardiac assist system for cardiac unloading and recovery. This type of ventricular assist device (VAD) will provide the optimal support for recovery for acute heart failure patients, and may be useful for a select group of chronic heart failure patients suppo ...

The practice of removing aircraft from service and disassembling parts of its structure for periodic inspection negatively impacts readiness and leads to high sustainment costs. Using Acoustic Ideas''''''''s uniquely powerful and versatile phased array technology we will develop a novel inspection method that does not require disassembly. Multiple layers, large thicknesses, dissimilar metals, seal ...

Nitrate is an important nutrient for crop production. Soils with excess nitrate amounts and shallow groundwater tables pose a high risk to nitrate leaching into drinking water supplies. A shortage of nitrate decreases agricultural productivity. Measurement of soil nitrate content is a tedious, time consuming, and expensive process. Currently, there are no commercial sensors for in-situ nitrate det ...

Both pyrolysis and oxidation steps have been considered as the key solid waste processing step for a Controlled Ecological Life Support System (CELSS). Pyrolysis is more amenable to handling mixed solid waste streams in a microgravity environment, but produces a more complex product stream. Oxidation (incineration) produces a simpler product stream, but the oxidation of mixed solids is a complex u ...

Under sponsorship of the Air Force SBIR program, the small business Advanced Fuel Research, Inc. (AFR) is developing an innovative sensor system to map the surface temperature of thermal barrier coated (TBC) turbine blades during operational testing of advanced military jet engines. Temperature mapping is a high priority capability needed to prove ceramic coatings as a reliable means to prevent bl ...

Gas turbine engine development requires sensors to measure gas path properties in engines during ground testing.  The data collected with these sensors are critical to the development of advanced engines with high performance, high efficiency, and low emissions.  While instrumentation is available to measure most of the important gas path properties, the drive toward higher turbine inlet tempera ...

A DNA sequencer for biometric applications will be developed. The system will enable rapid and low-cost identification of individuals and kinship verification using a self-contained and portable device. All process steps from DNA extraction to DNA sequencing will be automatically performed within the disposable single-use cartridge. This high-level of functional integration is made possible by Adv ...

DESCRIPTION (provided by applicant): Miniaturized DNA Sequencer for Identification of Microbial Pathogens Abstract. The goal of this project is develop a compact and inexpensive DNA sequencer based on the implementation of sequencing-by-synthesis chemistry on a droplet-based digital microfluidic cartridge. The proposed device would be capable of sequencing 10's to 100's of base pairs using an ine ...

DESCRIPTION (provided by applicant): Newborn screening is currently performed by collecting dried bloodspots from infants and then sending them to a lab for analysis. Lysosomal storage diseases alone number greater than 40 and there is an increasing necessity to screen for a number of disease conditions for which therapies are becoming available. Tandem mass spectrometry is an excellent multiplex ...