Award Data

DESCRIPTION (provided by applicant): Cardiac failure is the, largest single cause of mortality in the United States today. With an increase in the use of long-term cardiac assist devices, there is also a need for the short-term "bridge to recovery" application. This application is intended to provide a low-cost temporary support for patients whose heart is capable of recovering. This "patient scr ...

DESCRIPTION (provided by applicant): Digoxin is the first line pharmacologic therapy for CHF and AF. Digoxin increases cardiac contractility and blocks conduction through the AV node slowing the ventricular response to AF and thus slowing the rate of the beating ventricles permitting more time for the heart to fill. The recent Dig trial supports the use of digoxin in the treatment of CHF and the r ...

An interactive application that employs social interactions to teach key social conventions, including appropriate responses, reacting to body language and facial expressions, and the ability to ask for help to facilitate functioning in society

DESCRIPTION (provided by applicant): Current HIV-1 therapy suffers from inadequate viral load suppression due to poor compliance, resistance, and interactions with other drugs and can lead to spread of drug-resistant strains. The current drug cocktails need to include inhibitors of viral components that are likely to slow resistance development. One such target is the HIV-1 capsid, an essential vi ...

Emissions of volatile organic compounds (VOCs) and hazardous air polutants (HAPS are a serioud environmental issue. These pollutants are requlated to protect human health and encourage the development of better control technologies. Current technologies to control thses emissions, until better materials are developed, include destructive and/or recovery-based technologies. Implementation of ads ...

This project addresses two vital problems for long-term space travel activities: radiation shielding and hydrogen storage for power and propulsion. While both problems have been studied for many years, there is currently no satisfactory technology for providing adequate non-parasitic shielding. Even in low-Earth orbit, astronauts must be closely monitored for radiation exposure, and some mission ...

A number of high-energy laser weapons currently under development by and for the U.S. military will provide our armed forces with capabilities that are unmatched by conventional armaments. Laser weapons allow targets to be destroyed from remote locations without the delays associated with the transit of typical missiles and artillery shells. However, during engagement the laser radiation reflect ...

The innovation proposed is a flight-worthy optical sensor that will monitor propulsion system performance and health characteristics, including identifying the onset of combustion instability, in air-breathing engines such as turbojets and ramjets. It is an innovation for three reasons: 1) the sensing is performed in the hot exhaust flow at the back of the engine instead of at the flame-front in t ...

This Small Business Technology Transfer Phase I research project's objectives are to build and validate an artificial star simulation application for the study of astronomical objects, and to assess its commercial potential for the professional and serious amateur astronomer communities. The prevalence of modern light detectors has ushered in a golden age for astronomy due to their outstanding cha ...

DESCRIPTION (provided by applicant): Stroke is the third leading cause of death in the United States and is the number one cause of adult disability. It is estimated that this clinical condition results in a cost of $30-40 billion in the U.S alone. While a large number of therapeutic agents have been investigated for the treatment of ischemic stroke, only one agent is currently approved for marke ...