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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 21665 results
  1. A Novel Polymeric Percutaneous Heart Valve Prosthesis

    SBC: ABIOMED, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The objective of this SBIR program is the modification of a polymeric trileaflet heart valve to a valve prosthesis that can be delivered percutaneously as a transcatheter aortic valve replacement. Key innovations include improved durability and hemodynamic properties, lower manufacturing costs, and simplified delivery over existing transcatheter bioprosthetic v ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Minimally Invasive Pediatric VAD for Treatment of Acute Heart Failure

    SBC: ABIOMED, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The overall objective of this proposed program is the commercialization of the Pediatric Impella system, a minimally invasive ventricular assist device (VAD) for treatment of acute heart failure in pediatric patients. The device will be a less traumatic alternative to extracorporeal membrane oxygenation (ECMO), the current standard of care for these patients. T ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Antibacterial Agents That Target DNA Replication in Mycobacterium tuberculo

    SBC: Achillion Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Mycobacterium tuberculosis (MTB) is probably the most ubiquitous microbial pathogen in the world today infecting one-third of the total population and causing millions of active tuberculosis (TB) cases each year. The economic costs are substantial and more than one million people die of TB infections each year. Before the arrival of antimicrobial therapy, TB wa ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Low Thermal Resistance Integrated Package and Heat Sink for HEV IGBT Modules

    SBC: ADVANCED THERMAL TECHNOLOGIES            Topic: 06c

    There is a growing demand for power electronics that can operate under the high temperature and high power conditions that will be encountered in Hybrid Electric Vehicles (HEV). As the coolant temperature used to dissipate heat from electronics increases, the operation of power semiconductor devices such as Insulated Gate Bipolar Transistors (IGBTs) becomes severely limited in order that the safe ...

    STTR Phase I 2010 Department of Energy
  5. PM 2.5 Emissions Reduction for Two-Stroke Engines

    SBC: AERODYNE RESEARCH INC            Topic: TopicG

    Small particulate emissions, such as those that fall within the PM2.5 classification, have a substantial negative effect on air quality and human health. Significant sources of PM2.5 emissions are small two-stroke engines that are used in outdoor power equipment such as leaf blowers, chain saws, and string trimmers, as well as larger two-stroke engines used in recreational vehicles such as all-ter ...

    SBIR Phase I 2010 Environmental Protection Agency
  6. Recovery Act- Vaporization Cooling for IGCC Turbines

    SBC: AERODYNE RESEARCH INC            Topic: 04a

    Electrical power generation consumes a large fraction of the nations fossil fuel, notably coal, and produces significant CO2 emissions. Gas turbine based cycles such as IGCC are constrained by turbine component temperature limits, and consequently have potential for lower fuel consumption and emissions. A novel, highly effective technology for cooling rotating turbine components has been under exp ...

    SBIR Phase I 2010 Department of Energy
  7. Chemical Ionization Time-of-Flight Mass Spectrometer for Particle and Gas-Phase Organic Speciation

    SBC: AERODYNE RESEARCH INC            Topic: 32c

    Aerosol particles have important impacts on visibility, acid deposition, climate, and human health, although large uncertainties remain in quantifying their chemical composition and atmospheric transformations. A large fraction of the anthropogenic aerosol is generated from energy-related activities, and organic compounds are known to constitute a significant fraction of ambient aerosol mass. Re ...

    SBIR Phase I 2010 Department of Energy
  8. High Sensitivity SO2 Monitor using Quantum Cascade Laser IR Absorption

    SBC: AERODYNE RESEARCH INC            Topic: 32d

    SO2 is an important ubiquitous aerosol precursor with anthropogenic, biogenic and geogenic sources. The sulfate aerosol produced from atmospheric oxidation of SO2 has a negative radiative forcing component that is highly uncertain due to its direct and indirect effects. Due to its potency as a remote clean atmosphere aerosol precursor and its capability to modify cloud properties, SO2 is a `short ...

    SBIR Phase I 2010 Department of Energy
  9. Dual Quantum Cascade Laser System For Simultaneous Measurements of 13CH4 and CH3D Methan Isotopolgues

    SBC: AERODYNE RESEARCH INC            Topic: 30b

    Methane is the second most important atmospheric greenhouse gas after CO2 yet its global sources and sinks are still inadequately characterized. Monitoring the isotopic composition of atmospheric methane is one of the most promising approaches to closing the methane budget. Detailed process studies of isotopic fractionation associated with methane sinks and sources are also crucial. For both p ...

    SBIR Phase I 2010 Department of Energy
  10. Development of a method to multiplex ChIP-SEQ and ChIP-chip experiments

    SBC: AFFOMIX, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The immediate objective of our research is to generate a method that will enable researchers to multiplex Chromatin ImmunoPreciptation-Sequencing (ChIP-Seq) analysis in a single Next generation DNA sequencing run. In the to-be-developed method: i) a set of antibodies directed against specific DNA-binding proteins are uniquely bar-coded with a DNA 'ZipCode;' ii) ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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