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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Quantitative Methane Plume Imager for Localization and Flow Rate Estimation in Mines

    SBC: PHYSICAL SCIENCES INC.            Topic: NIOSH

    Project Summary Abstract NIOSH conducts activities to assure safe and healthful conditions for American workersThis proposed project addresses a NIOSH mission objective for innovative solutions that provide practical methods to identify and measure hazards at a reasonable cost in high risk occupationse gminingThe mining industry presents particularly challenging safety and health needsDespite well ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  2. Improving Human Performance through Neuroenhancement

    SBC: REJUVENATE BIO INC            Topic: SOCOM182002

    Special Operations Forces (SOF) are an integral aspect of the US military. SOF operators are among the most elite and highly qualified individuals in the U.S. military. As such, extraordinary physical and mental demands are placed upon them to excel in extreme environments for extended periods of time. This unrelenting cycle of combat deployments and intense pre-deployment training shortens the fu ...

    SBIR Phase I 2018 Department of DefenseSpecial Operations Command
  3. First-in-human study of MW151, a novel drug targeting neuroinflammation

    SBC: IMMUNOCHEM THERAPEUTICS LLC            Topic: NIA

    ABSTRACT Alzheimerandapos s diseaseADis one of the largest global public health crises facing us todayyet there are no effective therapies available to preventdelayor slow AD progressionDominant approaches based on a set of prevailing core hypotheses about druggable pathways and targets have failedThereforethere is a need for novel and alternative pathways distinct from those pursued over the past ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Visible light activated implant devices to prevent biofilm formation

    SBC: Sonata LLC            Topic: NCEZID

    Prevention of biofilms on invasive medical devices has the potential to significantly reduce hospital acquired infections and improve patient outcomesProsthetic joint infectionsPJIsacquired from orthopedic implantsoften the result of microorganism contamination on the implant surface during surgeryaffect patient recoveries and can lead to significant mortalitiesOne approach for reducing the incide ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  5. Optimization of small molecule SERCA2b activators to inhibit neuron loss in Alzheimer's disease

    SBC: NEURODON, LLC            Topic: NIA

    Alzheimer s diseaseADis an immense national public health burdenIt is theth leading cause of death in the US with overmillion Americans sufferingand costs of over $billion in health care and related expensesThis patient population is expected to almost triple over the nextyearsDespite this urgent needthere are currently no disease modifying agents approvedNeuron loss is the only physiological phen ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Rapid, Simple and Cost-Effective Detection of Human Cell Line Contamination

    SBC: Nuprobe Usa, Inc.            Topic: R

    Summary Cell line contamination and misidentification have dramatic repercussions in the field biomedical researchlargely contributing to the growing concerns about irreproducible results and posing a significant burden on the global biomedical research budgetWhile the general awareness about these issues has raised over the last yearscurrent authentication technologies such as short tandem repeat ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Web-based App to Alleviate Loneliness and Isolation in Older Adults at Home

    SBC: VIGOROUS MIND INC            Topic: NIA

    ABSTRACT Loneliness contributes to physical and psychological chronic illnessesfunctional decline and mortality in older adultsThe fast growing older population coupled with the worsening shortage of caregivers will soon present our nation with severe societal and economic challengesOlder adults often struggle to maintain quality of life and independence in the presence of chronic diseases and iso ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Astrocyte activation by small-molecule ADORA3 agonists: a novel therapy for Alzheimer's disease

    SBC: ASTROCYTE PHARMACEUTICALS INC.            Topic: NIA

    PROJECT SUMMARY Alzheimerandapos s diseaseADis an area of significant unmet need that creates a national burden of$billion annuallyAD is the leading cause of dementiaaffectingof Americans over the age ofDemographic shifts and the age related nature of AD will soon place this disease as the costliest health care expenditure in the U Swith a projected impact of $trillion per year byCurrent therapies ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. A practical platform for in-home remote monitoring of cognitive-frailty

    SBC: BIOSENSICS LLC            Topic: NIA

    AbstractCognitive frailtythe combined presence of physical frailty and cognitive impairmentis a strong and independent predictor of cognitive declineThe International Association of Gerontology and Geriatrics and the International Academy on Nutrition and Aging have recommended the use of cognitive frailty assessment to track the progression of mild cognitive impairmentMCItowards dementiaAlzheimer ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. The Development of a High Throughput Whole Brain Alzheimer's Disease Drug Screening Pipeline

    SBC: Tissuevision Inc            Topic: NIA

    Project Summary Alzheimer s diseaseADis a debilitating neurodegenerative disease affecting roughlyinpeople over the age ofInthe total cost of AD in the United States was estimated at $billion and is predicted to climb to $trillion by the yearDespite enormous efforts invested in finding a cureit has proven extremely difficult to develop treatments for ADContributing factors behind this difficulty i ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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