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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Develop predictive human cardiomyocyte-based all optical assay for cardiotoxicity

    SBC: Q-State Biosciences, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Develop predictive human cardiomyocyte based all optical assay for cardiotoxicity Cardiotoxicity is the leading cause of safety driven withdrawal a all stages and limitation of drug compounds The current cardiac safety paradigm nonclinical guidance ICH S B focuses on in vitro hERG assays which prove to be suboptimal in predicting a compoundandapos s cardioto ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Stem Cell Bioreactor for Cardiac Care

    SBC: Sentien Biotechnologies, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant The goal of this Fast Track Phase I II SBIR is to test a novel extracorporeal system for delivering mesenchymal stem cell MSC secretions to treat acute myocardial infarction MI We will use the Sentien proprietary extracorporeal delivery system to treat swine subjected to a clinically relevant model of MI The project specific aims are Simulated blood ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. FAST TRACK: IND Enabling Studies for Oral Cancer

    SBC: PRIVO TECHNOLOGIES, LLC            Topic: 102

    DESCRIPTION provided by applicant According to the Oral Cancer OC Foundation oral and pharyngeal cancer will cause deaths this year in the US killing roughly one person per hour Currently cisplatin CIS is at the forefront of platinum based chemotherapeutics for treating OC However its efficacy is often hindered by its significant systemic toxicity as a resut of traditional bolus ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. High Performance Switched Reluctance Generator Controller

    SBC: QUALTECH SYSTEMS, INC.            Topic: A15087

    This proposal describes a method to reduce the acoustic noise and torque ripple of a switched-reluctance machine by solving a multi-objective optimization problem. The physical limitations of the machine, namely voltage and temperature, are used as constraints, and these are related to the objectives of noise and torque variation. Electrical, mechanical, and thermal models are used to form an anal ...

    SBIR Phase I 2015 Department of DefenseArmy
  5. Category-Theoretic Tool for Manufacturing-related Information Integration

    SBC: CATEGORICAL INFORMATICS, INC.            Topic: 9010173R

    Categorical theory has recently been successfully applied to translate information from one computer system to another. Researchers at MIT have developed a prototype software tool based on category theory for solving information-integration programs. The tool has successfully solved small-scale information-integration problems including a problem identified by NIST about enriching the manufacturin ...

    SBIR Phase I 2015 Department of CommerceNational Institute of Standards and Technology
  6. High Performance Accelerated Graph Programming Enabled by Julia

    SBC: Julia Computing, Inc.            Topic: SB152004

    Julia Computing seeks to significantly enhance visualization, data and graph analytics at high performance speeds to provide information for actionable intelligence to DoD and commercial sectors. This SBIR will leverage the Julia computing language's flexibility and modern architecture to exploit parallelism available through a range of modern accelerators including many core architectures (e.g. ...

    SBIR Phase I 2015 Department of DefenseDefense Advanced Research Projects Agency
  7. A system to Predict and Analyze Novel and emerging Diseases Enabled by Models of Infection Conditions (PANDEMIC)

    SBC: CHARLES RIVER ANALYTICS, INC.            Topic: DHP15008

    Incidences of infectious disease pose serious threats to armed forces worldwide, risking the success of critical operations and can be responsible for the deaths of Warfighters. Current approaches attempt to reduce severity of disease impact to operational forces by detecting, monitoring, and treating infected personnel after exposure, but this does not effectively maintain and sustain force healt ...

    SBIR Phase I 2015 Department of DefenseDefense Health Agency
  8. Real-time Automated Ply Inspection (RTAPI)

    SBC: FLIGHTWARE INC            Topic: DLA152001

    Real-time Automated Ply Inspection (RTAPI) is a layup inspection system that determines if the layup produced by an Automated Fiber Placement (AFP) machine meets drawing requirements. This is performed in real-time, while the machine is laying composite tapes onto the mold at very high speed, providing several benefits. As a fully automated system it eliminates very slow and tedious manual inspect ...

    SBIR Phase I 2015 Department of DefenseDefense Logistics Agency
  9. Additive Manufacturing of Ceramics for Casting

    SBC: TRITON SYSTEMS, INC.            Topic: DLA152003

    The Defense Logistics Agency (DLA) seeks to drastically reduce costs and increase availability of cast parts.To this end, Triton Systems proposes to develop an innovative method for the fabrication of low cost manufacturing of ceramic cores and molds.Traditionally, ceramic molds and cores are expensive and have long lead times, but Triton proposes to develop the materials and methods to use Cerami ...

    SBIR Phase I 2015 Department of DefenseDefense Logistics Agency
  10. Measuring toxicant effects on cellular function in a microarray format

    SBC: CIENCIA INC            Topic: NIEHS

    DESCRIPTION provided by applicant The EPA maintains a Toxics Release Inventory of over toxic chemicals that are disposed or released from more than industrial sites in the United States The Department of Health and Human Services and USDA maintain a list of over select agents and toxins that pose a severe risk to both human animal and plant health These compounds represent only ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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