Award Data

This STTR Phase I project will develop and test a learning platform to facilitate independent, personal and enjoyable science education. The platform combines an engaging book, whose characters employ a fictional virtual environment to solve a mystery, with a complementary computer-based virtual environment to support games, explorations, and interviews with Expert Avatars (XAs), such as Albert Ei ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop technology to conserve scarce water resources and improve crop management practices. Agricultural production uses a great deal of water. In California alone, 80% percent of all water usage goes to agriculture. As communities expand and drought conditions develop, the competi ...

The broader impact/commercial potential of this Small Business Technology Transfer Phase I project is to improve the recycling rates and efficiency of lithium ion (Li-ion) batteries, as well as lower the cost of cathode materials for Li-ion batteries. This research project will accomplish these goals by recovering cathode material from a broad spectrum of Li-ion battery regardless of size, shape o ...

The broader impact/commercial potential of this Small Business Technology Transfer Research (STTR) Phase I project will be, if successful, enabling the development of the smallest Raman spectroscopy-capable fiber probe ever developed. The optimization of a smaller Raman-capable probe will improve a broad range of clinical applications such as coronary artery plaque diagnosis during cardiac angiogr ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be the microbial production by fermentation of a group of natural food colorants, called anthocyanins, which will benefit the environment, the food industry, and society as a whole. The fermentation production process provides a "green chemistry" approach to issues usually encountered in traditio ...

NASA's goals to explore deep space through manned missions requires development of self-sustaining life support systems. A diverse team from Freight Farms, Inc. have partnered with Clemson University to merge knowledge of sustainable farming with engineering expertise to create off-grid infrastructure for self-sustaining plant life that will assist NASA with their goals. Freight Farms' current pro ...

DESCRIPTION provided by applicant Triple negative breast cancers TNBCs account for of breast cancer deaths and lack targeted therapies Drs Sonenshein Mineva and Romagnoli and their co workers recently identified the non essential cell surface protein ADAM A Disintegrin and Metalloprotease as a pivotal promoter of breast tumor growth and metastasis and validated it as a target o ...

DESCRIPTION provided by applicant Hepatocellular carcinoma HCC is the most prevalent cancer in human population and will lead to over deaths in the United States this year alone However the molecular mechanisms driving hepatocellular carcinoma HCC growth and metastasis remain elusive and there is a huge unmet medical need to find new therapeutic targets We performed an unbiased ...

DESCRIPTION provided by applicant Drug resistance to HIV is a major threat to achieving long term viral suppression in HIV individuals Up to of newly infected individuals acquire HIV with resistance to at least one of the major antiretroviral classes and incomplete viral suppression and virologic failure are often associated with drug resistance Therefore current DHHS guideline recomme ...

DESCRIPTION provided by applicant Neuropathic pain is a serious health problem that affects millions of people worldwide and occurs in as much as of the general population The management of neuropathic pain in patients is complex with an estimated of individuals refractory to existing analgesic therapies The aging population the diabetes epidemic and the significant cohorts of can ...