Award Data

21CT and CUBRC propose CEDAR (Complex Event Discovery, Analysis, and Ranking), a robust framework to detect and analyze indicators of complex activities, such as an insurgent ambush observable via myriad of simple events in multiple sensor streams. CEDAR will provide a mapping from complex behavior, such as conducting an insurgent ambush or rebuilding trust in local communities, to simple event in ...

Intelligent Tutoring Systems (ITSs) functions as virtual tutors that adapt to student responses. Such ITSs, however, do not yield student learning improvements equivalent to students tutored by human instructors. Ascertaining Un-Reported Affect (AURA) is a closed-loop, platform-independent “front-end” for informing ITSs with near real-time inferences of student engagement and affect during lea ...

As the need to monitor ever-increasing amounts of information, the need to fact check continues to grow. It is important for analysts to stay ahead of the information curve; an analysis based on yesterday’s news may be erroneous, especially in the case of key information changes. Today, individual users must manage their own updates, which means logging into the wiki and checking the update lo ...

Cyber Network Operations is a critical new battlefield that holds asymmetric threats to U.S. military, technological, and economic dominance. 21CT’s Heuristic-Aware Anomaly Detection (HAAD) approach develops new behavioral threat detection algorithms that provide fast, effective, flexible, and adaptive defense. Many existing techniques rely on hardcoded signatures, making them brittle, expensive ...

21st Century Technologies’ (21CT) ACCESS (Automated Comparison and Clustering of Entity SignatureS) research effort addresses the issue of comparing entities such as human personas and networks, so that a more complete assessment of at-risk entities can be made within and across the various domains in which those entities interact. The Phase I effort of ACCESS will provide an effective similarit ...

DESCRIPTION (provided by applicant): The objective of this SBIR program is the modification of a polymeric trileaflet heart valve to a valve prosthesis that can be delivered percutaneously as a transcatheter aortic valve replacement. Key innovations include improved durability and hemodynamic properties, lower manufacturing costs, and simplified delivery over existing transcatheter bioprosthetic v ...

DESCRIPTION (provided by applicant): The overall objective of this proposed program is the commercialization of the Pediatric Impella system, a minimally invasive ventricular assist device (VAD) for treatment of acute heart failure in pediatric patients. The device will be a less traumatic alternative to extracorporeal membrane oxygenation (ECMO), the current standard of care for these patients. T ...

DESCRIPTION (provided by applicant): The importance of reducing the incidence of secondary injuries related to manual wheelchair propulsion is undisputed. Based on several research studies, approximately 50% of manual wheelchair users (MWU) report symptoms of repetitive strain injury (RSI) related to the demand on the upper extremity during propulsion and transferring tasks. A substantial effort ...

DESCRIPTION (provided by applicant): Mycobacterium tuberculosis (MTB) is probably the most ubiquitous microbial pathogen in the world today infecting one-third of the total population and causing millions of active tuberculosis (TB) cases each year. The economic costs are substantial and more than one million people die of TB infections each year. Before the arrival of antimicrobial therapy, TB wa ...

Research in silicon photonics has received much attention in recent years for its potential to utilize well developed silicon processing technology. A broad range of linear and nonlinear silicon photonic devices such as modulators, splitters, switches and detectors have been demonstrated. However, the most important challenge in silicon photonics thus far is the difficulty of making electrically p ...