Award Data

DESCRIPTION (provided by applicant): The objective of this proposed program is to develop a general purpose anastomotic device for large vessels and vascular grafts, based on a novel stapler design. The use of the device can provide an alternative procedure to the current manual suturing methods, with the potential of yielding anastomoses having better and more reproducible performance, and with r ...

DESCRIPTION (provided by applicant): The overall objective of this proposed program is the commercialization of an advanced intraventricular cardiac assist system for cardiac unloading and recovery. This type of ventricular assist device (VAD) will provide the optimal support for recovery for acute heart failure patients, and may be useful for a select group of chronic heart failure patients suppo ...

The practice of removing aircraft from service and disassembling parts of its structure for periodic inspection negatively impacts readiness and leads to high sustainment costs. Using Acoustic Ideas''''''''s uniquely powerful and versatile phased array technology we will develop a novel inspection method that does not require disassembly. Multiple layers, large thicknesses, dissimilar metals, seal ...

Nitrate is an important nutrient for crop production. Soils with excess nitrate amounts and shallow groundwater tables pose a high risk to nitrate leaching into drinking water supplies. A shortage of nitrate decreases agricultural productivity. Measurement of soil nitrate content is a tedious, time consuming, and expensive process. Currently, there are no commercial sensors for in-situ nitrate det ...

The proposed research program will develop a physics-based identification, modeling and risk management infrastructure for aeroelastic transonic flutter and limit-cycle oscillations (LCO). This capability will be built upon high fidelity state-of-the-art theoretical/computational methods as validated and verified by available experimental data bases, and will include (1) rapid flutter boundary det ...

The proposed work aims at developing techniques that will address the current limitations of Cartesian-based Navier-Stokes CFD schemes by exploring three promising methods of implementing improved wall boundary conditions. The three methods are based on: (1) the diamond stencil approach of Delanaye et al., (2) the extrapolation boundary condition work by Marshall and Ruffin, and (3) the Material P ...

Both pyrolysis and oxidation steps have been considered as the key solid waste processing step for a Controlled Ecological Life Support System (CELSS). Pyrolysis is more amenable to handling mixed solid waste streams in a microgravity environment, but produces a more complex product stream. Oxidation (incineration) produces a simpler product stream, but the oxidation of mixed solids is a complex u ...

Gas turbine engine development requires sensors to measure gas path properties in engines during ground testing.  The data collected with these sensors are critical to the development of advanced engines with high performance, high efficiency, and low emissions.  While instrumentation is available to measure most of the important gas path properties, the drive toward higher turbine inlet tempera ...

DESCRIPTION (provided by applicant): The goal of the present work is to demonstrate a label-free multiplexed immunoassay platform liver disease diagnosis. The method is to integrate multiple tests for serum antigens and antibodies onto a single disposable chip that could be used with the instrument for about the cost of one or a few current immunoassays that identify the presence of just one marke ...

DESCRIPTION (provided by applicant): We propose the development of a single-chip, multiplexed, label-free platform for Alzheimer's disease diagnosis and monitoring of protein markers in the cerebral spinal fluid (CSF). The Spectral Reflectance Imaging Biosensor is a label-free protein array technology that can monitor real-time binding label-free at more than 1000 locations simultaneously. A uniq ...