Award Data

This Small Business Innovation Research (SBIR) Phase II project concerns the development of an optical alloy composition sensor based on laser induced plasma spectroscopy. A key element of the sensor is the use of a microchip laser excitation source. The technology has the capability to detect industrially relevant compositions in steel alloys and possibly aluminum alloys. The Phase I results in ...

This Small Business Innovation Research Phase II project will develop a new analytical tool for characterizing drug delivery aerosols and powders. This instrument will be based on a previously developed aerosal mass spectrometer that provides real-time size distribution and chemical composition measurements for aerosol particles. During Phase I research, a new inlet for the aerosol mass spectromet ...

This Small Business Innovative Research (SBIR) Phase I project is to develop a compact and autonomous, high precision monitor for the potent greenhouse gases, methane and nitrous oxide. This proposal is submitted under the Geoscience Instrumentation subtopic (subtopic E) of the Electronics topic. The target molecules are currently detected with cw lead salt diode lasers. These lasers require cryog ...

This Small Business Innovation Research (SBIR) Phase I project addresses the accurate measurement of the composition and microphysics of atmospheric aerosols that have significant implications for global and regulatory environmental issues. This project would replace the quadrupole mass-spectrometer (QMS) with a compact time-of-flight mass spectrometer (TOFMS). This would enable the measurement of ...

This Small Business Innovation Research (SBIR) Phase I project proposes to develop a new intraoperative imaging probe based on a solid-state, compact readout sensor coupled to a high resolution, high light output converter. Nuclear Medicine imaging has been widely used to preoperatively image structures of interest for excisional biopsy. Radio-guided intraoperative procedures utilizing non-imaging ...

This Small Business Innovation Research (SBIR) Phase I Project proposes to design and construct a novel cell-based microfluidic platform for the discovery and development of therapeutic drugs. Utilizing state-of-the-art microfabrication techniques, micro-sensor and controller design, fluid handling and cell culturing techniques, the project seeks to address the shortcomings and bottlenecks of curr ...

This Small Business Innovation Research (SBIR) Phase I project will demonstrate the feasibility of a miniaturized fast-response oxygen sensor. Fuel efficiency of automotive engines and power generating systems improve when operated under lean-burn conditions. Oxygen monitoring in industrial processes promise higher productivity while effective fire fighting requires information regarding local co ...

This Small Business Innovation Research (SBIR) Phase I project proposes to demonstrate the feasibility of a miniaturized MEMS-based, reagent-less biological agent detector, capable of performing rapid assays for tens (or even hundreds) of analytes simultaneously, for detection of whole bacteria (or spores) with single bacteria/spore resolution. National defense against biological warfare agents a ...

This Small Business Innovation Research Phase I project will develop a highly conductive p-type AlGaN by construction of AlGaN superlattices. The material p-type AlGaN is key to many optoelectronic and some electronic semiconductor devices. Many characteristics of semiconductor devices containing p-type AlGaN (that is, power efficiency, maximum power, noise properties, maximum operating temperatur ...

This Small Business Innovation Research Phase I project intends to fabricate, and test a condensation nucleus counter (CNC) of the turbulent-mixing type, with a detection limit below 2 nm particle diameter, and able to measure the size distribution of aerosol nanoparticles. A novelty of this apparatus is that its super-saturation level can be adjusted quickly and accurately along a wide range. Thi ...