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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. VASCULAR STAPLER

    SBC: ABIOMED, INC.            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM IS TO DESIGN AND BUILD A STAPLER FOR PERFORMING END-TO-END AND END-TO-SIDE ANASTOMOSES ON MEDIUM TO LARGE VESSELS, AND FOR REPAIRING BLOOD VESSELS AND VASCULAR ANEURYSMS, AND TO DEVELOP A SURGICAL PROTOCOL FOR ITS USE. THE METHOD PROPOSED USES A SPECIAL STAPLER AND CONFIGURATION OF STAPLES WHICH MINIMIZESBLOOD CONTACT WITH THE STAPLES, DOES NOT RESTRICT THE FLOW OF BL ...

    SBIR Phase I 1988 Department of Health and Human Services
  2. Cannula System for "Bridge to Recovery" Cardiac Assist

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cardiac failure is the, largest single cause of mortality in the United States today. With an increase in the use of long-term cardiac assist devices, there is also a need for the short-term "bridge to recovery" application. This application is intended to provide a low-cost temporary support for patients whose heart is capable of recovering. This "patient scr ...

    SBIR Phase I 2005 Department of Health and Human Services
  3. ULTRAMINIATURE IMPLANTABLE ELECTRICAL CONNECTOR

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  4. Social-Simentor: Interactive Simulation e-Learning Tool to Develop Interpersonal Skills for Individuals with Cognitive Disabilities to Improve Hiring and Retention

    SBC: Access Tech            Topic: N/A

    An interactive application that employs social interactions to teach key social conventions, including appropriate responses, reacting to body language and facial expressions, and the ability to ask for help to facilitate functioning in society

    SBIR Phase I 2005 Department of Education
  5. Capsid assembly inhibitors for the treatment of AIDS

    SBC: Achillion Pharmaceuticals, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Current HIV-1 therapy suffers from inadequate viral load suppression due to poor compliance, resistance, and interactions with other drugs and can lead to spread of drug-resistant strains. The current drug cocktails need to include inhibitors of viral components that are likely to slow resistance development. One such target is the HIV-1 capsid, an essential vi ...

    SBIR Phase I 2005 Department of Health and Human Services
  6. HEPATOCYTE DIRECTED MAGNETIC RESONANCE CONTRAST AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  7. Enzymatic Pleurodesis for Malignant Pleural Effusions

    SBC: AERIS THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I SBIR application is presented by Aeris Therapeutics, Inc. of Woburn, MA. It will examine the feasibility of using a novel enzyme based-system to produce safe, clinically-effective pleurodesis for treatment of malignant pleural effusions. Preliminary data, summarized in this application, suggest that an enzymatic system has the potential for bei ...

    SBIR Phase I 2005 Department of Health and Human Services
  8. Breath Analysis using Quantum Cascade Lasers

    SBC: Aerodyne Research, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The analysis of components in human breath is a powerful non-invasive technique for the diagnosis and monitoring of asthma, cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). The presence of elevated levels of nitric oxide (NO), carbon monoxide (CO), and ethane (C2H6) in the breath have been identified as biomarkers of these diseases, wh ...

    SBIR Phase I 2005 Department of Health and Human Services
  9. PERIDONTAL DISEASE IS ONE OF THE MOST WIDESPREAD MEDICAL PROBLEMS FACING THE NATION TODAY.

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    PERIDONTAL DISEASE IS ONE OF THE MOST WIDESPREAD MEDICAL PROBLEMS FACING THE NATION TODAY. CRUCIAL TO THE SUCCESSFUL TREATMENT OF THIS DISEASE IS EARLY DETECTION AS WELL AS CAREFUL MONITORING OF THE PROGRESS OF THE PERIODONTAL THERAPY. THERE ARE, HOWEVER, FEW EFFECTIVE APPROACHES TO THIS PROBLEM AND, FOR THE PRESENT, PERIODONTISTS MUST STILL RELY VERY HEAVILY ON DENTAL X-RAYS. UNFORTUNATELY, WHILE ...

    SBIR Phase I 1985 Department of Health and Human Services
  10. IMPROVED RFLP ANALYSIS FOR GENETIC LINKAGE MAPPING

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    ONE OF THE MOST ACTIVE AND CHALLENGING FIELDS IN MOLECULAR BIOLOGY TODAY IS THE GENETIC STUDY OF EUKARYOTIC SYSTEMS. ONE RAPIDLY GROWING AREA IN THIS FIELD IS THE STUDY OF RESTRICTION FRAGMENT LENGTH POLYMORPHISMS (RFLPS). THIS PROCEDURE USES RADIOLABELED HYBRIDIZATION TECHNIQUES AND AUTORADIOGRAPHY TO CONSTRUCT A HUMAN GENETIC LINKAGE MAP BY IDENTIFYING GENETIC MARKERS ALONG THE GENOME. THE PARTI ...

    SBIR Phase I 1988 Department of Health and Human Services
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