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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. VASCULAR STAPLER

    SBC: ABIOMED, INC.            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM IS TO DESIGN AND BUILD A STAPLER FOR PERFORMING END-TO-END AND END-TO-SIDE ANASTOMOSES ON MEDIUM TO LARGE VESSELS, AND FOR REPAIRING BLOOD VESSELS AND VASCULAR ANEURYSMS, AND TO DEVELOP A SURGICAL PROTOCOL FOR ITS USE. THE METHOD PROPOSED USES A SPECIAL STAPLER AND CONFIGURATION OF STAPLES WHICH MINIMIZESBLOOD CONTACT WITH THE STAPLES, DOES NOT RESTRICT THE FLOW OF BL ...

    SBIR Phase I 1988 Department of Health and Human Services
  2. Cannula System for "Bridge to Recovery" Cardiac Assist

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cardiac failure is the, largest single cause of mortality in the United States today. With an increase in the use of long-term cardiac assist devices, there is also a need for the short-term "bridge to recovery" application. This application is intended to provide a low-cost temporary support for patients whose heart is capable of recovering. This "patient scr ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. ULTRAMINIATURE IMPLANTABLE ELECTRICAL CONNECTOR

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  4. Social-Simentor: Interactive Simulation e-Learning Tool to Develop Interpersonal Skills for Individuals with Cognitive Disabilities to Improve Hiring and Retention

    SBC: Access Tech            Topic: N/A

    An interactive application that employs social interactions to teach key social conventions, including appropriate responses, reacting to body language and facial expressions, and the ability to ask for help to facilitate functioning in society

    SBIR Phase I 2005 Department of Education
  5. Capsid assembly inhibitors for the treatment of AIDS

    SBC: Achillion Pharmaceuticals, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Current HIV-1 therapy suffers from inadequate viral load suppression due to poor compliance, resistance, and interactions with other drugs and can lead to spread of drug-resistant strains. The current drug cocktails need to include inhibitors of viral components that are likely to slow resistance development. One such target is the HIV-1 capsid, an essential vi ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Nanodroplet PCR Lab-Chip for Clinical Pathogen Detection

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Rapid and accurate detection and identification of pathogens is crucial for the effective management and treatment of infectious disease. While molecular diagnostic techniques including PCR are a promising approach for rapid and sensitive detection of pathogens, they suffer from a number of technical drawbacks which have slowed their acceptance in the clinic. ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. HEPATOCYTE DIRECTED MAGNETIC RESONANCE CONTRAST AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  8. Enzymatic Pleurodesis for Malignant Pleural Effusions

    SBC: AERIS THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I SBIR application is presented by Aeris Therapeutics, Inc. of Woburn, MA. It will examine the feasibility of using a novel enzyme based-system to produce safe, clinically-effective pleurodesis for treatment of malignant pleural effusions. Preliminary data, summarized in this application, suggest that an enzymatic system has the potential for bei ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Breath Analysis using Quantum Cascade Lasers

    SBC: AERODYNE RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): The analysis of components in human breath is a powerful non-invasive technique for the diagnosis and monitoring of asthma, cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). The presence of elevated levels of nitric oxide (NO), carbon monoxide (CO), and ethane (C2H6) in the breath have been identified as biomarkers of these diseases, wh ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Discovery of Peptide-based Bone Morphogenic Protein Mimetics

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In this proposal, we present a novel approach for the identification and immobilization of a BMP mimetic. We plan to use phage display technology to identify peptides that mimic BMP-like signaling of the BMP receptors. These peptides will be linked to a previously identified high-affinity, collagen-binding peptide. The resulting hybrid molecule will allow contr ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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