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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Crowding Information Collection and Dissemination System

    SBC: Arcon Corporation            Topic: 171FT1

    Train car crowding is a key issue resulting in passenger dissatisfaction and degraded transit service. One reason for train car crowding is an uneven distribution of passengers among the train cars which results in overcrowding of certain cars while leaving other cars sparsely occupied. If passengers waiting at a station are informed about the expected crowding levels in the arriving train, they c ...

    SBIR Phase I 2017 Department of Transportation
  2. Detection of THC Use in Drivers

    SBC: Giner, Inc.            Topic: 171NH1

    Driving under the influence of marijuana, the most commonly used illicit drug in the United States is reported to double the risk of crash involvement. As marijuana decriminalization and legalization measures continue to gain acceptance, the potential number of drivers using marijuana could rise dramatically, necessitating new ways for law enforcement to combat the pursuant increase in drug relate ...

    SBIR Phase I 2017 Department of Transportation
  3. A Robust Railway Track Crack Detection System Using Thermal Signatures

    SBC: Migma Systems Inc.            Topic: 171FR2

    In Phase I, Migma Systems propose to develop a robust system for detection of railway track surface cracks. Automated railway inspection is critical for ensuring the safety of public transportation. Rails often break under trains and broken tracks can lead to train derailment. In Phase I, we will make a prototype sensor with low power microprocessor, IR camera, GPS and temperature/humidity sensor ...

    SBIR Phase I 2017 Department of Transportation
  4. Driver breath measurement of marijuana intoxication by infrared spectroscopy

    SBC: N2 Biomedical, LLC            Topic: 171NH1

    The intoxicating effects of marijuana are of public safety concern. With the expected increase in the use of this substance it is important to provide law-enforcement officials with a simple driver test for its detection. Because of the presence of the intoxication agent tetrahydrocannabinol (THC) vapor in the exhaled breath of marijuana users, it is possible to confirm marijuana intoxication via ...

    SBIR Phase I 2017 Department of Transportation
  5. Genome Mining the Full Diversity of the Actinomycete Biosynthetic Universe for Neomorph Antibiotic Discovery

    SBC: WARP DRIVE BIO, LLC            Topic: NIAID

    ABSTRACT To combat multidrug resistant bacterial infections novel classes of antibiotics with new mechanisms of action are desperately required Genome mining for novel natural products is quickly replacing traditional approaches to antibiotic discovery Warp Drive Bio has sequenced over actinomycete strain genomes from diverse sources worldwide and our proprietary genomic database conta ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Selection of a device for intranasal administration of a mucosal vaccine for HSV

    SBC: Biomedical Research Models, Inc.            Topic: R

    Globally an estimated of the human population is infected with HSV including andgt of the U S adult population Genital herpes is associated with an increased risk of HIV acquisition and transmission of HSV infection can cause neonatal herpes with high infant mortality HSV infection in the adult population has increased substantially in the past two decades despite the availabil ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A Rapid Low Cost Point of Care Diagnostic for detection of Zika virus RNA

    SBC: L2 DIAGNOSTICS, LLC            Topic: NIAID

    ABSTRACT Zika virus ZIKV has rapidly emerged and spread through South and Central America the Caribbean and Puerto Rico since its last outbreak in Micronesia in Transmitted by the mosquito Aedes sp its forecasted spread will have a major impact on the Southeast U S Most ZIKV infections remain asymptomatic or present with non specific rash and fever therefore they have been difficult ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Harnessing Genomic Information to Engineer Combinatorial Biosynthesis of a Large Polyketide Natural Products Library

    SBC: WARP DRIVE BIO, LLC            Topic: NIAID

    Abstract Natural products have outstanding pharmaceutical pedigree approximately of FDA approved small molecule drugs are derived from plant bacterial or fungal sources To discover new natural products Warp Drive Bio has assembled an enormous proprietary and searchable database of microbial genomes and biosynthetic gene clusters To date our database comprises genomes sequenced ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Screening for rAAV transduction enhancers

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    ABSTRACT Recombinant adeno associated virusrAAVis a promising gene delivery vector for therapeutic and vaccine applicationsbut its low transduction efficacy currently limits its utilityThe primary reasons for low transduction efficacy are as followsiinefficient trafficking of the rAAV genome to the nucleusiiinefficient host cell mediated synthesis of double stranded DNA from the single stranded ge ...

    SBIR Phase I 2017 Department of Health and Human Services
  10. Optical Dosimeter guided Photodynamic Therapy

    SBC: Physical Sciences Inc.            Topic: 102

    Photodynamic Therapy PDT is a promising modality for cancer treatment Oxygen molecules in the metastable singlet delta state O are believed to be the species that destroys cancerous cells during PDT Despite the benefit of targeted PDT that kills tumors selectively with minimum effect on surrounding healthy tissues at the present time it is difficult if not impossible to predict the res ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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