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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. IN VIVO COINCIDENCE XRF MEASUREMENTS FOR HEAVY METALS

    SBC: ABIOMED, INC.            Topic: N/A

    X-RAY FLUORESCENCE (XRF) IS THE MOST PRECISE METHOD OF MEASURING BODY AND ORGAN BURDENS OF HEAVY METALS IN VIVO. HOWEVER, THE REQUIRED PRECISION FOR SCREENING OF CHRONICALLYLOW-LEVEL-EXPOSED POPULATIONS FOR THESE METALS, IN PARTICULAR LEAD AND MERCURY, IS BETWEEN 5 AND 20 TIMES GREATER THAN ACHIEVABLE BY CURRENT METHODS. THIS PROJECT DESCRIBES AN INNOVATIVE VARIATION OF XRF THAT CAN PROVIDE AN IMP ...

    SBIR Phase I 1990 Department of Health and Human Services
  2. CONTINUOUS, AUTOMATED CONTROL OF IABP TIMING

    SBC: ABIOMED, INC.            Topic: N/A

    THE EFFECTIVENESS OF INTRA-AORTIC BALLOON PUMP (IABP) THERAPY IS DEPENDENT ON PHYSIOLOGICAL AND PHYSICAL VARIABLES, PERHAPS THE MOST IMPORTANT OF WHICH IS THE SETTING OF IABP TIMING OF INFLATION AND DEFLATION RELATIVE TO THE CARDIAC CYCLE. THE OPTIMIZATION OF TIMING IS CURRENTLY HANDLED MANUALLY, DELEGATED TO A PUMP TECHNICIAN OR PERFUSIONIST, AND IS UPDATED ANYWHERE FROM SEVERAL TIMES AN HOUR TO ...

    SBIR Phase I 1990 Department of Health and Human Services
  3. PEDIATRIC BODY LEAD BURDEN BY X-RAY FLUORESCENCE

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  4. NEW FLOW CYTOMETRY TECHNOLOGIES FOR CLINICAL HEMATOLOGY

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  5. LONG-TERM CENTRIFUGAL VENTRICULAR ASSIST DEVICE

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  6. A PERIODONTAL TEMPERATURE AND DEPTH PROBE

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  7. AN OPTIMAL LASER SOURCE FOR SMALL-DIAMETER VASCULAR ANASTOMOSES

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  8. HEPATOCYTE DIRECTED MAGNETIC RESONANCE CONTRAST AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    DISEASES OF THE LIVER ARE A MAJOR HEALTH PROBLEM. DIAGNOSTIC TECHNIQUES TO PREDICT LIVER FAILURE ARE INTERPRETABLE IN TERMS OF OVERALL LIVER FUNCTION, NOT IN TERMS OF ANATOMIC STRUCTURE. ANATOMICAL INFORMATION ON LIVER HAS BEEN OBTAINED BY USING RADIOACTIVE COLLOIDS. THESE MATERIALS ARE TAKEN UP BY KUPFFER CELLS (3% OF LIVER MASS) AND NOT BY HEPATOCYTES (90% OF LIVER MASS), THE MAIN METABOLIZING C ...

    SBIR Phase II 1990 Department of Health and Human Services
  9. STABILITY FORCE PLATFORM

    SBC: Advanced Mechanical Technology, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  10. BIOLOGICAL MATERIALS SEPARATION BY CONDUCTIVE MEMBRANES

    SBC: AST PRODUCTS, INC.            Topic: N/A

    MEMBRANE TECHNOLOGY FOR BIOSEPARATION HAS EVOLVED RAPIDLY OVER THE LAST FEW YEARS. THE DEVELOPMENT OF NEW POLYMERIC MATERIALS AND HIGHLY ASYMMETRIC MEMBRANES ARE TWO OF THE MAJOR REASONS FOR THIS EVOLUTION. DESPITE THESE ADVANCES, HOWEVER, THE USE OF MEMBRANE-BASED PROCESSES FOR BIOSEPARATIONS IS STILL LIMITED BY BOTH MEMBRANE FOULING AND GEL FORMATION DUE TO PROTEIN ADSORPTION. THESE PROBLEMSSEVE ...

    SBIR Phase I 1990 Department of Health and Human Services

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