Award Data

FORAY bioscience Inc. Phase I USDA-NIFA-SBIR-009301 Topic 8.1 2023PI: Dr. ASHLEY BECKWITHCEO FORAY bioscience IncE-mail: ash@foraybio.comAdvancing tissue culture in tree species for use in climate adaptation breedingproduction of cultured tree products1 Project SummaryDemand for forest products is growing but global forests are shrinking by ~15 billion trees per year.Sourcing inefficiencies exacer ...

Our water air soil farms and forests depend on birds as vital natural resources. Birds consumeinsects pollinate plants disperse seeds and maintain wetlands. Unfortunately transmission linecollisions kill 57 million birds annually in the United States. Installing markers that help birdssee and not hit power lines can decrease bird collisions by more than 70%. Today powerlinemen use bucket trucks an ...

EmergingDx Inc. in collaboration with Michigan State University will leverage on-goingprograms and their collective expertise to develop a rapid low-cost multiplexed colorimetricquantitative loop-mediated isothermal amplification (qLAMP) microfluidic based diagnostic devicewith high sensitivity and selectivity for screening reproductive fluids/gametes to be used forbreaking the vertical transmissi ...

PROJECT SUMMARYTitle:Field-Deployable Crispr-Based Diagnostics For Improved Biosecurity In AquaculturePD:Fiore Elizabeth Institution:Sherlock Biosciences Inc.Rapid and accurate health assessment of farmed animals is critical to US aquaculture andagriculture. It is hindered by the cost time and technical expertise required for standard diagnosticmethods resulting in reduced capacity for disease con ...

OTHER PROJECT INFORMATION – Unit 7 – Project Summary/Abstract This project addresses the growing need for medications for cannabis use disorder (CUD) which, in the absence of approved medications, is a major focus of NIDA’s mission. Currently available cannabinergic-based treatments for CUD include the directly acting CB1 agonists, e.g., Δ9-THC or nabilone, which have been reported to reduc ...

PROJECT SUMMARY: Herpes Simplex Virus (HSV) infections are common, infecting more than half of the world’s population. While most cases of genital herpes are caused by HSV type 2 (HSV-2), it is estimated that more than 150 million people aged 15-49 have genital HSV type 1 (HSV-1) infections. Although several vaccines have been evaluated for preventing/treating HSV infections, none have received ...

Project Summary Crohn’s disease is a debilitating and chronic inflammatory disorder of the gastrointestinal tract characterized by aberrant healing and intestinal stricturing. In the US, rt500,000 patients suffer from Crohn’s disease and over 30,000 patients are newly diagnosed each year. No curative treatments exist. Instead, current treatments focus on managing symptoms and reducing the occu ...

Project Summary The value of computational chemistry to commercial drug discovery is now well-established. Virtual screening (including molecular docking) now jumpstarts most discovery efforts. Tools such as molecular dynamics and free energy perturbation are increasingly used to inform the later stages of lead refinement. The growing importance of computational structure-based methods has influen ...

ABSTRACT The United States is experiencing a major mental health crisis. Per recent reports in the New York Times and The Washington Post, the gap between need and access to behavioral health services is rapidly increasing. There is an urgent need to solve both the access and quality problems with behavioral healthcare. With COVID and other stressors, 76% of surveyed employees are reporting at lea ...

Project Summary/Abstract Retinal neovascularization (RNV) is a major cause of vision loss in retinopathy of prematurity (ROP), diabetic retinopathy (DR) and retinal vein occlusion. In the US, about 16,000 of premature infants are affected by ROP annually and about 4.1 million adults years have DR. Complications of conventional treatments suggest an unmet need for new therapies. The long-term objec ...