Award Data

DESCRIPTION (provided by applicant): Electrochemical Home Monitoring System for Lithium Blood Level Lithium in the form of lithium carbonate is an important pharmacological treatment option in bipolar disorder (BD) and other conditions. However, lithium has a narrow therapeutic treatment range and its use requires careful monitoring of a patient's lithium blood level, particularly during the ...

A major threat to U.S. personnel stationed abroad are high levels of toxins that may be present in the local food supply as a result of unregulated pesticide use and the prevalence of toxic industrial chemicals and heavy metals in the environment.Rapid analytical methods are needed that are capable of identifying these threats in food at levels that exceed military exposure guidelines.Triton Syste ...

Special Operation Forces (SOF) operate in remote locations for extended periods and often with out support of conventional military medical support. Improved body armor has protected most vital areas but there are still a number of penetrating injuries to the upper and lower extremities. During the care under fire and tactical field care phase of tactical combat casualty care, SOF medics and opera ...

This Phase II proposal addresses the design, development, fabrication and test of a wideband body worn antenna for threat warning and Direction Finding. This effort will build on Phase I results and tailor/optimize the antenna’s performance for the DF environment, by building a detailed electromagnetic computer model of the antenna. The performance of the antenna will be demonstrated at the pr ...

Protonex will develop a quiet, durable, high-energy source which is able to power auxiliary electrical equipment for SOCOM operations. It must be able to withstand a harsh operational environment and be lightweight, compact and man portable. Protonex proposes to develop a quiet Auxiliary Power Unit (APU) that will meet all the energy, power and other requirements for this application. This syst ...

An electric power source is needed that is two-man portable or lighter, operates on logistics fuels (JP-8, diesel), is quiet, and has a low thermal signature. We propose the MICE (Miniature Internal Combustion Engine) generator that is currently being developed by Aerodyne Research to deliver 500 W electrical power using logistics fuels. The design for this MICE generator will weigh less than 16 ...

DESCRIPTION (provided by applicant): Cardiac failure is the, largest single cause of mortality in the United States today. With an increase in the use of long-term cardiac assist devices, there is also a need for the short-term "bridge to recovery" application. This application is intended to provide a low-cost temporary support for patients whose heart is capable of recovering. This "patient scr ...

DESCRIPTION (provided by applicant): This Phase I SBIR application is presented by Aeris Therapeutics, Inc. of Woburn, MA. It will examine the feasibility of using a novel enzyme based-system to produce safe, clinically-effective pleurodesis for treatment of malignant pleural effusions. Preliminary data, summarized in this application, suggest that an enzymatic system has the potential for bei ...

DESCRIPTION (provided by applicant): The analysis of components in human breath is a powerful non-invasive technique for the diagnosis and monitoring of asthma, cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). The presence of elevated levels of nitric oxide (NO), carbon monoxide (CO), and ethane (C2H6) in the breath have been identified as biomarkers of these diseases, wh ...

DESCRIPTION (provided by applicant): Murine models of cancer now have an essential role in formulating modern concepts of carcinogenesis and metastasis, and provide us with a realistic means of developing and evaluating new diagnostic and therapeutic techniques. Moreover, transgenic and knock-out techniques for manipulating the genome allow us to tailor animal models that accurately recapitulate ...