Award Data

"Current glass-based transparent armor has two major deficiencies: 1) It is very heavy, and therefore can compromise performance and helicopter transportability of vehicles; and 2) It is very thick, and therefore can compromise visual signature of vehicles. Advanced technology ceramic transparent armor removes both these deficiencies and provides a twofold improvement in performance, but costs 6-1 ...

Physical Sciences Inc. (PSI) proposes to utilize an innovative LWIR hyperspectral technology coupled with advanced data processing algorithms for non-contact, standoff detection of liquid/solid contaminants on surfaces. The technology will address the US Army"s need for fast, on-the-move, non-contact detection of ground contamination during reconnaissance missions. The Phase I effort demonstrated ...

Many protein-based drugs have limited efficacy due to a short half-life or require intravenous delivery because of low bioavailability. Extend Biosciences is developing proprietary carrier molecules that allow proteins to access an intrinsic transport pathway for efficient delivery to the vascular space and then maintain a sustained presence in circulation. This novel technology would be of partic ...

Systems & Technology Research (STR) together with our partner, The Ohio State University ElectroScience Laboratory (OSU/ESL), is pleased to provide this proposal to develop foliage propagation modeling algorithms, measurements and techniques to support new communications concepts. Our innovative approach to this problem will combine efficient computational electromagnetic methods (CEM) that captur ...

Next generation sequencing technologies are allowing researchers to rapidly and accurately interrogate the genomic content of microbiomes. Advances in our understanding of the human microbiome are likely to lead to the use of next generation sequencing as a diagnostic tool to identify the existence and precise genotype of pathogens and virulence genes. Likewise, our ability to engineer microbes us ...

Efficient and accurate indexing is fundamental to the Big Data enterprise, but traditional indexing techniques are often foiled by noise and missing information. Aptima proposes Phase II of CERTAIN (Certainty Enrichment via Relational and Temporal Analyti

Gen9 is developing a DNA synthesis platform that aims to produce synthetic DNA products at an industry leading length, price point and turnaround time. In this Phase II proposal we outline our approach to extend the processes we developed during the Phase

Polestar Technologies Inc. proposes a Phase I Small Business Innovation Research project to develop a chemical sensor for detection of chemical-warfare agents. The designed sensor combines selectivity of Molecularly-Imprinted Polymer (MIP) with sensitivity of single-layer graphene sheet. Detection will be based on radio frequency (RF) based impedance. The proposed sensor will be robust, highly dep ...

Akita Innovations proposes to develop the next generation of voltage-sensitive dyes for cellular bioelectricity measurements by engineering electric field sensitivity into a class of highly fluorescent dyes which heretofore have not been used for this purpose. The much higher brightness of these dyes will improve the sensitivity of the voltage measurements. Akita will also develop a method of ta ...

In this Small Business Innovation Research program, we will develop a new class of nanosensors that are high contrast, ultrabright and fast optical voltage-indicators from diamond nanocrystals for neural activity imaging applications in vitro and in vivo. These photostable and cytocompatible diamond nanosensors will be able to monitor the bioelectric states and sub-threshold events in human cells ...