Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. DMX: Enabling Blind Source Separation for Hearing Health Care

    SBC: SPEECH TECHNOLOGY/APPLIED RESEARCH CORP.            Topic: NIDCD

    DESCRIPTION provided by applicant Typical biological environments comprise complex mixtures of signals from multiple biological and environmental sources Some sources contain critical information that researchers seek to acquire other sources are distractions that interfer with data acquisition Common acoustic environments are an important example a significant segment of the aging US popul ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Rapid and On-site Monitoring of Urinary Arsenic Metabolites

    SBC: Giner, Inc.            Topic: NIEHS

    DESCRIPTION provided by applicant Giner Inc proposes a portable inexpensive and rapid response monitor for arsenic speciation in urine Arsenic species excreted in urine are reflective of exposure to toxic arsenic species and therefore this monitor will be a valuable tool in medical diagnostics and epidemiological studies by allowing determination of arsenic exposure by a technique that is ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Device for Measuring Capillary Blood Flow and the Onset of Shock

    SBC: Radiation Monitoring Devices, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Hemorrhagic shock is a major cause of death in emergency departments and trauma centers Currently there is no clinically accepted quantitative monitor of the onset of hemorrhagic shock Death from hemorrhagic shock results from diminished capillary blood flow and the resultant failure of the body to oxygenate major organs The long term goal of this proposal ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Novel Inhibitors Targeting Early Steps of Human Cytomegalovirus Replication

    SBC: MICROBIOTIX, INC.            Topic: R

    DESCRIPTION provided by applicant Human cytomegalovirus HCMV infection is a major cause of morbidity and mortality in immunosuppressed patients especially recipients of solid organ or bone marrow transplants HCMV infection of neonates is associated with deafness mental retardation and mortality Although five anti viral drugs GCV val GCV CDV PFA Foscarnet have been approved and lice ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Mobile Health App to Reduce Diabetes in Latina Women with Prior Gestational Diabe

    SBC: Environment And Health Group, Inc.            Topic: NIMHD

    DESCRIPTION provided by applicant Hispanic women have the highest lifetime risk for type diabetes T DM A window of opportunity for preventing T DM exists for women with pregnancies complicated by gestational diabetes mellitus GDM Women with prior GDM face increased risk of T DM Hispanic women are at increased risk of GDM and those with GDM have higher relative risks for developing T D ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Multifunctional nanoformulations for diagnostic imaging of atherosclerosis

    SBC: SIGNABLOK, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Despite advances in cardiovascular care atherosclerosis remains the leading cause of mortality in the United States and worldwide A vast majority of cardiovascular events such as stroke or myocardial infarction result from rupture or erosion of vulnerable atherosclerotic plaques These plaques are characterized by high and active macrophage content Current i ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Fluorescence Lifetime Dynamics to Understand Brain Neural Activities and Behavior

    SBC: ChiSquare Bioimaging, LLC            Topic: 500

    DESCRIPTION provided by applicant The overall objective of the proposed project is to create a compact robust and easy to use device that is capable of sensitive and quantitative detection of fluorescence lifetime indicators of physiological and biochemical dynamics deep in the brain of a freely moving mouse In contrast to fluorescence intensity based methods fluorescence lifetime can delin ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. An Open Source Precision Medicine Platform for Cloud Operating Systems

    SBC: CUROVERSE, INC.            Topic: 400

    DESCRIPTION provided by applicant Rapid improvements in DNA sequencing and synthesis have the potential to usher in a new era of precision medicine To realize this vision however we must re imagine the computational and storage infrastructure used to manage and extract actionable results from the massive data sets made possible by widely available advances in DNA sequencing and synthetic bio ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Portable Gas Perfusion System for Pancreas Preservation

    SBC: Giner, Inc.            Topic: 200

    DESCRIPTION provided by applicant Pancreatic islet transplantation ITx is an emerging treatment for a subset of Type diabetics for which standard insulin therapies are insufficient I is a promising alternative to pancreas transplantation since ITx has significantly less surgical risk and a less toxic immunosuppression regimen Enhanced organ preservation via the proposed technology has th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Optical Surgical Probe for Assessing Human Oral Mucosa Graft Vascularization

    SBC: Radiation Monitoring Devices, Inc.            Topic: NIDCR

    DESCRIPTION provided by applicant Devastating and disfiguring facial injuries can result from gunshot wounds and motor vehicle accidents as well as from cancer surgeries of the head and neck or breast The most advanced reconstructive procedures involve distant transfer of tissue including bone periosteum skin muscle and vasculature followed microsurgical anastomosis of pre existing blood ve ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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