Award Data

"Current glass-based transparent armor has two major deficiencies: 1) It is very heavy, and therefore can compromise performance and helicopter transportability of vehicles; and 2) It is very thick, and therefore can compromise visual signature of vehicles. Advanced technology ceramic transparent armor removes both these deficiencies and provides a twofold improvement in performance, but costs 6-1 ...

Triton Systems Inc.(Triton), together with our partner Technical Products Inc. (TPI) will conduct a feasibility study to evaluate options for armoring non standard commercial vehicles (NSCV) in an unobtrusive fashion using austere mechanical facilities corresponding to expedient basing in the area of operations. Triton has wide experience in metallic, ceramic and composite armoring solutions and ...

High speed combatant craft utilized by SOCOM, such as the Riverine (SOC-R), use pumped raw water to provide engine cooling for the twin marine diesel engines. While raw water provides an essentially limitless heat sink, it often contains debris which can clog engine strainers, causing the engines to overheat. Thus, engine performance, as well as maintenance, is negatively affected by the use of th ...

? DESCRIPTION (provided by applicant): Alcoholic liver disease is a highly prevalent and costly condition affecting millions of people globally. Alcohol results in high morbidity and mortality an is responsible for nearly 4% of all deaths worldwide. Despite the tremendous societal and economic burden, there is no approved therapeutics for alcoholic liver disease. Instead, the standard of care ...

Abstract Persistent injury to the liver can cause chronic inflammation and dysregulated deposition of extracellular matrix (ECM), leading to accumulation of fibrotic scar tissue and eventually cirrhosis. While fibrosis is a normal wound healing response, in excess, it can further injure tissue and activate pro-fibrotic cells, resulting in a positive feedback loop. Scar tissue is not static, ECM re ...

DESCRIPTION (provided by applicant): The measurement of testosterone levels is central to the diagnosis of androgen disorders in men and women. Circulating testosterone is bound largely to sex hormone binding globulin (SHBG) and albumin; only the unbound or free fraction is biologically active. Therefore, in conditions that affect SHBG concentrations, such as aging, obesity, and diabetes, the dete ...

DESCRIPTION (provided by applicant): An estimated 5.4 million Americans had Alzheimer's disease in 2012 and a 50% increase in this number is expected by 2030. The majority of these patients (70%) will live at home where they receive 75% of their care frominformal caregivers, unpaid individuals such as family members, friends, and neighbors. These caregivers provide valuable services, often a ...

DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is characterized by progressively worsening dementia eventually leading to death. It affects over five million people in the United States and costs the healthcare system over 200 billion per year. Currently there is no available therapy for slowing, reversing or preventing the disease. There is strong evidence suggesting that AD ...

DESCRIPTION (provided by applicant): Advanced Medical Electronics (AME) and our partners propose a minimally-invasive system for continuous monitoring of potassium. Measurement of blood levels of potassium is important in clinical medicine. Abnormalities of potassium, common in heart and kidney disease, can be aggravated by many medications used to treat these disorders leading to arrhythmias and ...

DESCRIPTION (provided by applicant): Fungal infections, particularly in immunocompromised patients, are a serious and growing problem. Although antifungal therapeutics have improved greatly, failures and relapse are common. Aspergillus fumigatus is a primary cause of these infections in several patient populations: transplants, leukemics, genetic deficiencies such as chronic granulomatous disease ...