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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  2. Measuring the Concentration of Host-cell Proteins in Biomanufacturing Using Silicon Nanowire Array Sensors

    SBC: Advanced Silicon Group            Topic: NA

    Our innovation is a low cost, sensitive, quantitative biosensor that can detect many biomarkers on the same chip. Our sensor consists of vertically aligned silicon nanowires. The silicon nanowires’ high surface area to volume ratio makes them sensitive to the environment around them and can thus lead to high sensitivity detection. Each of the nanowires can be functionalized to be sensitive to ei ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  3. High-Throughput Single-Nanoparticle Magnetic Analysis Platform Using Diamond Magnetic Imaging

    SBC: Quantum Diamond Technologies Inc            Topic: NA

    Magnetic nanoparticles are widely-used tools over a range of industries, but have particularly powerful biomedical applications for clinical and research diagnostics, clinical therapy, and basic life science research. Many of these applications require consistent sources for magnetic nanoparticles with narrow distributions of magnetic properties, but no technology is now commercially available for ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  4. High-Throughput Single-Nanoparticle Magnetic Analysis Platform Using Diamond Magnetic Imaging

    SBC: Quantum Diamond Technologies Inc            Topic: 90109

    Magnetic nanoparticles are powerful tools over a wide range of industries, but have particularly powerful biomedical applications for clinical and research diagnostics, clinical therapy, and basic life science research. These applications require consistent sources for magnetic nanoparticles with narrow distributions of magnetic properties, but no technology is now commercially available for manuf ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology
  5. Pre-concentrator for Capture of Trace Fluorocarbons

    SBC: XPLOSAFE, LLC            Topic: 90108

    While fluorocarbons are released in relatively small amounts, they can have half-lives in the atmosphere as long as 50,000 years. However, they have extremely high global warming potential relative to other greenhouse gases, so that even small atmospheric concentrations can have large effect on global temperatures. For this reason, monitoring atmospheric concentrations of these compounds, identify ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology
  6. A Category-theoretic Tool for Manufacturing Information Integration

    SBC: CATEGORICAL INFORMATICS, INC.            Topic: 90101

    Category theory has recently been successfully applied to translate information from one computer system to another. Researchers at MIT have developed a prototype software tool based on category theory for solving information-integration programs. The tool has successfully solved small-scale information-integration problems including a problem identified by NIST about enriching the manufacturing s ...

    SBIR Phase II 2016 Department of CommerceNational Institute of Standards and Technology
  7. ZnS Scintillator for High Resolution X-ray Imaging at 9keV

    SBC: CERANOVA CORPORATION            Topic: DMEA15B001

    Novel scintillator materials are needed to address the requirements of fast, high resolution x-ray microscopy, including higher stopping power and light yields. Achieving the required high efficiency and high spatial resolution is challenging and depends strongly on the scintillator characteristics. Knowledge of the details of the trap states can lead to significantly reduced afterglow and fast ...

    SBIR Phase I 2016 Department of DefenseDefense Microelectronics Activity
  8. New Sensor for 9 keV HRXM

    SBC: Radiation Monitoring Devices, Inc.            Topic: DMEA15B001

    The use of penetrating radiation such as x-rays allows probing materials for their internal structure through direct imaging methods in a non-destructive way. X-rays as more penetrating and with shorter wavelengths than visible light allow imaging internal structures with better resolution. The resolution of details can reach nm sizes. This is realized in High Resolution X-ray Microscopy (HRXM). ...

    SBIR Phase I 2016 Department of DefenseDefense Microelectronics Activity
  9. System Architecture Recovery and Analysis (SARA)

    SBC: BlueRISC Inc            Topic: OSD153001

    BlueRISCs proposed solution takes the form of a binary-level toolkit that provides a fundamentally new approach to enable the extraction of a vulnerability-focused architectural model as well as an interactive security-focused visualization framework from an embedded software binary without any source-code knowledge.It is based on a conceptual framework that is able to identify and model external ...

    SBIR Phase I 2016 Department of DefenseOffice of the Secretary of Defense
  10. Situation Aware Network Deception Management (SANDMan)

    SBC: Boston Fusion Corp.            Topic: OSD153002

    Defending against state-of-the-art cyber attacks such as Advanced Persistent Threats requires the capability to counter the adversarys actions after they have already gained a foothold within our networks. Network deception techniques, working in conjunction with normal cyber defense methods, can alter the underlying attack process, making it more difficult, time consuming, and cost prohibitive fo ...

    SBIR Phase I 2016 Department of DefenseOffice of the Secretary of Defense

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