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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  2. Measuring the Concentration of Host-cell Proteins in Biomanufacturing Using Silicon Nanowire Array Sensors

    SBC: Advanced Silicon Group            Topic: NA

    Our innovation is a low cost, sensitive, quantitative biosensor that can detect many biomarkers on the same chip. Our sensor consists of vertically aligned silicon nanowires. The silicon nanowires’ high surface area to volume ratio makes them sensitive to the environment around them and can thus lead to high sensitivity detection. Each of the nanowires can be functionalized to be sensitive to ei ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  3. High Density Semi-Auto Closed Cycle Cryoprober II

    SBC: Microxact, Inc.            Topic: NA

    High density wafer scale cryogenic probing solution for testing at 4.5K temperatures or below is needed for testing and characterization of devices and circuits employing superconducting electronic components (such as used for quantum processing, high speed classical processing, magnetic field sensors, etc.) as well as for testing of various particle and light detectors for astronomy, aerospace, d ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  4. High-Throughput Single-Nanoparticle Magnetic Analysis Platform Using Diamond Magnetic Imaging

    SBC: Quantum Diamond Technologies Inc            Topic: NA

    Magnetic nanoparticles are widely-used tools over a range of industries, but have particularly powerful biomedical applications for clinical and research diagnostics, clinical therapy, and basic life science research. Many of these applications require consistent sources for magnetic nanoparticles with narrow distributions of magnetic properties, but no technology is now commercially available for ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  5. Bimetallic Zero Valent Iron Composites for In Situ Remediation

    SBC: AxNano, Llc            Topic: NA

    The EPA estimates that one out of every four Americans lives within three miles of a hazardous waste site. Recent advanced materials developments have driven increased use of In Situ Chemical Reduction (ISCR) remediation in the US and globally. Nanoscale Zero Valent Iron (NZVI) holds great potential for ISCR due to its low cost and high capacity for degrading halogenated compounds. However, two ma ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  6. High Density Semi-Auto Closed Cycle Cryoprober

    SBC: Microxact, Inc.            Topic: 90104

    High density wafer scale cryogenic probing solution for testing at 4.5K temperatures or below is needed for testing and characterization of devices and circuits employing superconducting electronic components (such as used for quantum processing, high speed classical processing, magnetic field sensors, etc.) as well as for testing of various particle and light detectors for astronomy, aerospace, d ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology
  7. High-Throughput Single-Nanoparticle Magnetic Analysis Platform Using Diamond Magnetic Imaging

    SBC: Quantum Diamond Technologies Inc            Topic: 90109

    Magnetic nanoparticles are powerful tools over a wide range of industries, but have particularly powerful biomedical applications for clinical and research diagnostics, clinical therapy, and basic life science research. These applications require consistent sources for magnetic nanoparticles with narrow distributions of magnetic properties, but no technology is now commercially available for manuf ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology
  8. Bimetallic Zero Valent Iron-Carbon Composites for In Situ Remediation: Improving Particle Lifetime, Reactivity and Transport

    SBC: AxNano, Llc            Topic: 90501

    The Environmental Protection Agency (EPA) estimates that one out of every four Americans lives within three miles of a hazardous waste site. Recent developments in advanced treatment materials has led to improvements driving increased use of In Situ Chemical Reduction (ISCR) at Superfund sites in the US and other contaminated zones around the world. Nanoscale Zero Valent Iron (NZVI) holds great po ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology
  9. A Category-theoretic Tool for Manufacturing Information Integration

    SBC: CATEGORICAL INFORMATICS, INC.            Topic: 90101

    Category theory has recently been successfully applied to translate information from one computer system to another. Researchers at MIT have developed a prototype software tool based on category theory for solving information-integration programs. The tool has successfully solved small-scale information-integration problems including a problem identified by NIST about enriching the manufacturing s ...

    SBIR Phase II 2016 Department of CommerceNational Institute of Standards and Technology
  10. System Architecture Recovery and Analysis (SARA)

    SBC: BlueRISC Inc            Topic: OSD153001

    BlueRISCs proposed solution takes the form of a binary-level toolkit that provides a fundamentally new approach to enable the extraction of a vulnerability-focused architectural model as well as an interactive security-focused visualization framework from an embedded software binary without any source-code knowledge.It is based on a conceptual framework that is able to identify and model external ...

    SBIR Phase I 2016 Department of DefenseOffice of the Secretary of Defense

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