List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Bioactive Polymer Designed for Cardiac Assist Devices

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the development of a novel, bioactive polymer for use in ventricular assist devices (VAD), and other long-term blood contacting implantable devices. Although VADs are becoming an important therapeutic option for patients in heart failure, serious problems persist secondary to thromboembolic complications and continue t ...

    SBIR Phase I 2003 Department of Health and Human Services
  2. An Artificial Myocardium for Pediatric Support

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the commercialization of a pediatric ventricular assist device (VAD). Although, VADs, both implantable and paracorporeal, have become an important surgical option for adult patients with myocardial failure unresponsive to less aggressive therapy, no VADs are commercially available for short-term use in children or smal ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. An Improved Prosthetic Bioactuator

    SBC: ADA Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Innovations in battery technology and microelectronics are now finding wide acceptance in the design of new prosthetic and orthotic appliances, while the actuators used to produce motion and force in these devices remain essentially unimproved. The overall goal of this multi-phase, expanded SBIR project is to adapt a new class of "active" materials--developed t ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. Powered Orthoses for Augmenting Upper Limb Functionally

    SBC: ADA Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): According to the U.S. Bureau of the Census, approximately 7.7 million people over the age of 15 report they are unable to lift or carry even 10 pounds with their arms because of neuromuscular impairments. Extensive research suggests that "powered orthoses" could provide great benefit to many of these individuals. Comprised essentially of an orthotic brace fitt ...

    SBIR Phase I 2003 Department of Health and Human Services
  5. New Agents That Inhibit Fatty Acid Accumulation

    SBC: ADIPOGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Although weight loss is the most effective treatment for type 2 diabetes, current methods for reducing weight typically are insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop and license novel the ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. Activators of Adipocyte Fatty Acid Oxidation

    SBC: ADIPOGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Existing drug and dietary treatments for obesity are only modestly effective. An approach that is very likely to be effective in treating obesity and with a good side effect profile is a drug that acts directly on lipid metabolism in the fat ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. Combination of GM-CSF with TKR gene therapy

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Combined gene therapy (Herpes Simplex Virus Thymidine Kinase + Anti-herpetic Prodrug) and radiation therapy (TKR therapy) is a novel approach in the armamentarium against cancer. This radio-gene therapy combination creates a new spatial co-operation whereby two local treatment modalities have demonstrated enhanced local and metastatic tumor control and prolong ...

    SBIR Phase I 2003 Department of Health and Human Services
  8. Biothreat Detection with Improved Background Rejection

    SBC: Aerodyne Research, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The Quartz Crystal Microbalance (QCM) is a well-established technology for quantifying small changes in mass. The long-term objective of this program is to improve the QCM so that it is suitable for use as a field test for the common, foodborne bacteria. To do this, we will modify the standard quartz crystal (QC) used in the QCM so as to increase its background ...

    SBIR Phase I 2003 Department of Health and Human Services
  9. Multiplex polony genotyping

    SBC: AGENCOURT BIOSCIENCE CORPORATION            Topic: N/A

    (Revised Abstract) Description: The ascertainment of millions of SNPs in the human genome, characterization of haplotype blocks and development of improved SNP-based linkage panels has fueled the need for accurate, efficient, and low cost SNP genotyping technologies to support genetic inheritance and disease association studies. The overall goals of this proposal are to develop and test a novel m ...

    SBIR Phase I 2003 Department of Health and Human Services
  10. Cellular Microarrays for in vitro toxicology screens

    SBC: AKCELI, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The studies outlined in this proposal are the first steps towards the establishment of a high throughput in vitro toxicology screen using mammalian cells. Toxicological screens are a critical component of the drug discovery process but are often employed late in the process due to the constraints of cost and throughput. The enablement of valid toxicology scr ...

    SBIR Phase I 2003 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government