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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Developing a novel system combining cognitive assessment with PASCALL FDA-cleared intraoperative anesthesia EEG brain monitor to prevent postoperative neurocognitive disorders in aging patients
SBC: PASCALL Systems, Incorporated Topic: NIAEach day, more than 100,000 patients undergo general anesthesia in the United States. The current practice of general anesthesia is prone to over-sedating patients, either due to the lack of brain monitoring or using brain monitors with inaccurate indices. Over-sedation (at 28% incidence) contributes to perioperative neurocognitive disorders (PNDs) in elderly population (≥65yrs). The cost of PND ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Membrane repair as a therapeutic intervention for treating Becker Muscular Dystrophy
SBC: MYOFINITY BIOSCIENCES INC Topic: NIAMSPROJECT ABSTRACTThe goal of this combined Phase I/II SBIR project is to accomplish key milestones in commercializing a protein therapeutic for Becker muscular dystrophy (BMD) that will enhance the repair capacity of muscle cell sarcolemmal membranes compromised by mutations in the dystrophin gene that reduce the expression level or function of the dystrophin protein. Many mutations in the dystroph ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Integrated Ferrite Inductors and Transformers for Power Electronics with Ultra-low SWAP-C
SBC: WINCHESTER TECHNOLOGIES LLC Topic: A16020State-of-the-art power electronics use discrete components such as power magnetic inductors and transformers operating at < 1MHz, which suffer from a large SWAP-C (size, weight, power consumption, and cost). It has been challenging to achieve simultaneously high inductance, compact size, and high quality factors at 1~300MHz for integrated power electronics. In the completed Phase II Army STTR Phas ...
STTR Phase II 2023 Department of DefenseArmy -
Development of a Urine Test for At-Home Monitoring of Blood Phe Levels for PKU
SBC: CIRCA BIOSCIENCE LLC Topic: NICHDPROJECT SUMMARY/ABSTRACT This project proposes the development of technologies to provide low-cost monitoring of phenylalanine (Phe) levels in the blood by a simple, noninvasive, at-home urine test, in order to enable daily monitoring by individuals with phenylketonuria (PKU). Also known as phenylalanine hydroxylase deficiency, PKU is a rare inborn error of metabolism that occurs in the US at a fr ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Developing Active Stimulation and Monitoring Technologies to Optimize Pain and Nociception Management During Regional Anesthesia, General Anesthesia, and Post-Operative Care
SBC: PASCALL Systems, Incorporated Topic: 106Project Summary Surgery and acute post-operative pain are major contributors to persistent pain, chronic pain, and opioid dependence. Currently, there are no products on the market in the United States that can be used to monitor surgical nociception. Existing products use indicators that are susceptible to intraoperative influences such as blood loss, anesthetic drugs and antihypertensives. This ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Developing a virtual reality guided acupuncture imagery treatment for Chronic low back pain
SBC: MASSACHUSETTS NEURO TECHNOLOGY, INC. Topic: NCCIHProject Summary Low back pain (LBP) is one of the most common reasons for physician visits in the USA. A substantial number of chronic LBP (cLBP) patients do not adequately respond to current treatment options. Thus, the development of new treatments for cLBP is urgently needed. The use of imagery to treat illness, including chronic pain, is one of the oldest medical practices. Although still unde ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Glycan biomarker panels in liquid biopsies for predicting treatment response in lupus nephritis
SBC: GLYCOPATH INC Topic: 400Lupus nephritis (LN), an immune complex-mediated glomerulonephritis, affects up to two-thirds of patients with systemic lupus erythematosus. Despite standard treatment protocols, progression of the most aggressive forms of LN (class III and IV) to end-stage renal failure remains high. Thus, there is a need for biomarkers of therapeutic response that would allow physicians to make better-informed t ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Phase 1 Trial to Assess Safety and Immune Effects of Xenon Gas in Healthy Human Subjects
SBC: General Biophysics LLC Topic: NIAPHASE II APPLICATION(STTR Program PAS-22-197) “Phase 1 Trial to Assess Safety and Immune Effects of Xenon Gas in Healthy Human Subjects” ABSTRACTAlzheimer’s disease (AD) is one of the most prevalent neurodegenerative disorders. Emerging evidence shows that homeostatic dysregulation of the brain immune system, especially that orchestrated by microglia, plays a significant role in the onset an ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Programming Metabolically Fit TILs for Immunotherapy
SBC: LIPO-IMMUNO TECH LLC Topic: NCIABSTRACT Advances in molecular biology and genetic engineering have led to the design and use of modified T cells recognize tumors to achieve significant tumor control upon adoptive cell transfer (ACT) to patients. These T cells are either transduced with tumor antigen reactive T cell receptors (TCR), or chimeric antigen receptors (CARs). Recently, a surge in studies with neo-antigen reactive T ce ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Improved Technology to Treat Drug-Resistant Bacterial Infections
SBC: TRITON SYSTEMS, INC. Topic: A21CT010Bacterial infections are particularly significant for military personnel in situations where there may be a long delay between the injury and treatment at a hospital or clinic. The development of an effective, portable light-based system which can operate in both military hospitals and far-forward situations is proposed. The proof-of-concept prototype developed in Phase I will be refined to be mor ...
STTR Phase II 2023 Department of DefenseArmy