Award Data

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is aimed at improving healthcare patient outcomes, potentially saving lives, and decreasing healthcare costs. The Drug Quality and Security Act of 2013 set stricter manufacturing standards on sterile injectable compounded medications that have closed many third party suppliers, thus creating s ...

This Small Business Innovation Research (SBIR) Phase II project will support the technological refinement and concomitant commercialization of the first accurate and portable instrument that can perform in the field nondestructive test for hardness, strength and ductility of existing infrastructure. The material properties measured include yield strength, work hardening exponent and ultimate tensi ...

This project proposes to develop an innovative approach to improve and sustain math educators' problem solving teaching skills. Despite the expectations placed on math teachers by the Common Core State Standards, most are insufficiently prepared to teach students how to become critical thinkers. Much of this problem is due to limited pedagogical skills of teachers in providing adequate problem sol ...

This Small Business Innovation Research (SBIR) Phase II project will address the challenge of fouling on membranes used in biopharmaceutical processing. The successful application of this coating would enable increase in the membrane lifetime and product yield of various production streams as less of the valuable compounds remain trapped in the membrane. This can increase production capacity for l ...

DESCRIPTIONprovided by applicantRecent data indicate that a substantial proportion of adultsyears of age and older are engaging in unsafeat risk drinkingeither based on the amount of alcohol they drink or alcohol use combined with other comorbidities or medicationsSeveral brief interventions to address the problem of excessive drinking in the elderlydesigned mainly for in person deliverymost in pr ...

The broadlongterm goal of this project is consistentstandardized diagnostic testing of surgicalspecimens by immunohistochemistryIHCThe methods to achieve this goal are well understood in thefield of clinical laboratory testingstandardization of reagents and protocolsautomation toreduce human errorsandthe use of standardized controls to provide test performance feedbackOver the last two decadesthe ...

PROJECT SUMMARY ABSTRACTImage guided surgery using invisible near infraredNIRlight is in the midst of a renaissanceMultiple commercial imaging systemsincluding Curadel s state of the art FLAREsystemare available for preclinicalveterinaryand human surgeryHoweverthe ultimate success of the field will depend on innovative NIR fluorophores that solve important clinical problemsCuradel has invented a n ...

ABSTRACT TuberculosisTBcaused by the bacterial pathogen Mycobacterium tuberculosisMtbremains a leading cause of death in the world today despite the availability of therapeutic drugs for more than sixty yearsThe disease also exacts a significant economic toll in countries where it is prevalentoften in poorer areas of the worldMultidrug resistant TBMDR TB and XDR TBis an increasing problemwith near ...

Radionuclide guided intraoperative probes increase the specificity of tissue biopsiesenable minimalaccess incisionsreduce inpatient hospital utilizationand contribute to improved patient recoveryAt presentmost such probes on the market are non imagingand provide no ancillary information of surveyed areassuch as clear delineations of malignant tissuesOur goal is to develop a revolutionary new imagi ...

Summary Abstract IntroductioniCare will provide e ectivehome based vision therapy through a motivating action based video game that inspires adherence in patients as young asyears oldThe proposed Phase IIB e ort supports development of the commercial systemcloud based tools for providers and patientsestablishment of e cacy and safetyand federal regulatory approvalProblem to be addressedConvergence ...