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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Dip and Read Nanosensor for Calcium Ion Measurement in Sea Water

    SBC: Polestar Technologies, Inc.            Topic: 822R

    The topic (8.2.2R) requires the capability for enabling high sensitive/high precision measurements of calcium concentrates in seawater. The proposal aims to demonstrate the feasibility of a novel high sensitive nanosensor that can be used to determine very low concentrations of calcium in seawater in the presence of large backgrounds calcium concentration. The sensor approach will use the benefi ...

    SBIR Phase I 2012 Department of Commerce
  2. Low Friction hybridSil Coatings for Preventing Vehicle Rollover on Concrete Barriers

    SBC: Nanosonic Inc.            Topic: 121FH1

    The objective of this DoT SBIR program is to establish a technical foundation enabling the rapid commercial integration of low friction HybridSil™ coatings on concrete barriers for drastic reductions in vehicle rollover potential. Phase I coatings would have immediate utility within a broad spectrum of concrete barriers designs with readily spray or paint depositions capabilities in traffic env ...

    SBIR Phase I 2012 Department of Transportation
  3. Socket Pressure Monitoring System

    SBC: Liberating Technologies, Inc.            Topic: 84133S1

    The goal of this Phase 1 project is to identify changes in residual limb volume in amputees and to warn the user when these changes may lead to potential problems. One cause of residual limb pain in amputees is improper prosthetic socket fit, causing a range of mild to unbearable pressures. Residual limbs can change shape over long timeframes which can change the interface between the socket and s ...

    SBIR Phase I 2012 Department of Education
  4. The Intelligent Brace: A Compliance Monitoring System for Scoliosis

    SBC: Liberating Technologies, Inc.            Topic: 84133S1

    The goal of this project is to provide real-time monitoring and data logging to help both the patient and clinician determine if and when a scoliosis brace is being worn effectively. Despite widespread use of bracing for treatment of scoliosis, its efficacy remains unproven. Studies have indicated that user compliance is a large factor in the efficacy of scoliosis brace treatment. Two factors comp ...

    SBIR Phase I 2012 Department of Education
  5. Quieting of Continuous Miner Scrubber Fan Noise

    SBC: AVEC, Inc.            Topic: NIOSH

    DESCRIPTION (provided by applicant): This proposal targets a specific mission of NIOSH and the current SBIR solicitation: hearing loss prevention for mine workers. The main objective of this work is to reduce the noise radiated by Continuous Miners (CM). Since CMs are responsible for about 30% of noise exposures above permissible levels [MSHA, 2006], reducing the noise in this machine would have a ...

    SBIR Phase I 2012 Department of Health and Human Services
  6. CSF Tau Biomarker-guided Development of Hsp90 Inhibitors for Alzheimer's Disease


    DESCRIPTION (provided by applicant): Research and Related Other Project Information Item 7. Project Summary/Abstract Neurodegeneration in Alzheimer's disease (AD) may result from deposition of A as plaques in brain tissue. However, less effort has been made to elucidate the role of tau- containing neurofibrillary tangles (NFTs) in AD. Accumulating evidence suggests that tau containing NFTs i ...

    STTR Phase I 2012 Department of Health and Human Services
  7. Point-of-Care Diagnostic Test for Entamoeba histolytica Cysts

    SBC: TECHLAB, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The NIAID Category B priority pathogen Entamoeba histolytica is a public health threat, especially as a cause of diarrhea in travelers to and immigrants from endemic areas, men who have sex with men, and children in thedeveloping world where it is in the top 5 causes of severe diarrhea. It is also a biodefense threat to water and food supplies due to its resist ...

    STTR Phase I 2012 Department of Health and Human Services
  8. Targeted Imaging Mass Spectroscopy for Biomarker Detection in Human Tissues

    SBC: PROVIA BIOLOGICS            Topic: NCI

    DESCRIPTION (provided by applicant): Biomarkers are measured in patient tissue biopsies to refine diagnosis, and to guide therapy. For a patient, this means receiving the therapy or drug most likely to work while avoiding the expense and toxic side effectsof alternatives. In pathology, a long-standing problem is that the most accurate methods for biomarker detection in tissues require extraction a ...

    STTR Phase I 2012 Department of Health and Human Services
  9. Devices enabling improved light delivery for photodynamic therapy of oral cancer

    SBC: LUCIFICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Oral cancer is a devastating disease that impacts 640,000 people worldwide. Though treatment with photodynamic therapy can be effective with significantly less morbidity than alternative therapies, problems arising fromless than optimal light delivery to the oral cavity have hindered its widespread application. The goal of the proposed research is to provide a ...

    STTR Phase I 2012 Department of Health and Human Services
  10. A Small Molecule to Activate Cetuximab to Kill K-RAS Mutant Colorectal Tumors


    DESCRIPTION (provided by applicant): In the United States colorectal cancer (CRC) is the third leading cause of cancer mortality. Surgery is the primary treatment for early stage CRC; but adjuvant therapy is usually needed in advanced disease. Approximately 55% of CRC patients have metastatic disease for which the prognosis is poor despite incremental improvements due to introduction of irinotecan ...

    STTR Phase I 2012 Department of Health and Human Services

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