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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. 12-lead MRI-Compatible ECG for physiological monitoring and scanner synchronizati

    SBC: E-TROLZ, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): This SBIR project aims to develop an MRI-compatible 12-lead ECG system. Such a system will provide greatly improved physiological monitoring inside the MRI, which is important for imaging severely ill patients (stroke, spine, patients with ischemic histories), and is also key to future MRI-guided interventions and surgeries. Current MRI-compatible ECG monit ...

    SBIR Phase I 2011 Department of Health and Human Services
  2. 2 MICRON FIBER LASER FOR SKIN REJUVENATION

    SBC: Cynosure, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1998 Department of Health and Human Services
  3. A Bioactive Prosthetic Vascular Graft

    SBC: BIOSURFACES, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are primarily comprised of polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Unfortunately, these grafts continue to have high failure rates due to secondary complications associated with acute thromboses and incomplete, unregulated cellular prol ...

    STTR Phase II 2011 Department of Health and Human Services
  4. A Clinical Decision Support Tool for Electronic Health Records

    SBC: Inflexxion, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): Substance abuse treatment is often complicated by problems such as depression, family and interpersonal conflicts, and legal issues. When these issues are addressed with effective, evidence-based treatments (EBTs), outcomes improve. To improve the quality of addiction treatment, experts have called for the adoption of a continuing care management approach, invo ...

    SBIR Phase I 2011 Department of Health and Human Services
  5. A device for rapid, painless, bedside muscle evaluation of children

    SBC: Myolex Inc            Topic: NINDS

    DESCRIPTION (provided by applicant): Our goal is to provide neurologists and other clinicians a method for the rapid, painless, non-invasive evaluation of children with neuromuscular disease. Pediatric neuromuscular disorders include muscular dystrophies, spinal muscular atrophy, and inflammatory myositis, and affect well over 100,000 children in the United States alone. Present-day clinical m ...

    SBIR Phase I 2011 Department of Health and Human Services
  6. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Cancer is America's second leading cause of death. Many approved cancer drugs, such as bortezomib (Velcade), are cytotoxic agents that kill normal cells as well as tumor cells. Therapeutic benefit depends on tumor cellsbeing more sensitive than normal cells, thereby allowing clinical responses to be achieved at relatively safe drug doses; however, damage t ...

    STTR Phase I 2011 Department of Health and Human Services
  7. A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming

    SBC: BARRON ASSOCIATES, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Convergence disorders and refractive amblyopia are among the most common and treatable vision problems seen in general optometric clinical practice. Oce- and home-based vision therapy (OBVT and HBVT, respectively) are standard treatments for such disorders. Recent advances in computerized video therapies that emulate vision therapy exercises performed in the op ...

    SBIR Phase II 2011 Department of Health and Human Services
  8. A NOVEL BIS-INDOLE COMPOUND AGAINST CATHETER COLONIZATION

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Infections associated with medical devices can be serious and even fatal. Catheter colonization and production of a biofilm on the surface of a catheter shortly after implantation are normally the prelude for infections. A number of antimicrobial-treated catheters have been developed to combat these infections, however, many of them have limited clinical effica ...

    STTR Phase I 2011 Department of Health and Human Services
  9. A ONE WEEK SUSTAINED RELEASE OF CLONAZEPAM

    SBC: BIOTEK, INC.            Topic: N/A

    N/A

    SBIR Phase I 1998 Department of Health and Human Services
  10. A point-of-care device for generating nitric oxide for inhalation

    SBC: WHALEN BIOMEDICAL, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Nitric oxide (NO) gas was considered to be a highly toxic pollutant as recently as the 1980s. It is now recognized to be an important messenger molecule in mammalian physiology. Inhaled NO is currently used to treat approximately 25,000 patients per year in this country with pulmonary hypertension. It is safe, effective, but costly. Published studies in which t ...

    SBIR Phase I 2011 Department of Health and Human Services

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