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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 57514 results
  1. Optical Dosimeter guided Photodynamic Therapy

    SBC: Physical Sciences Inc.            Topic: 102

    Photodynamic Therapy PDT is a promising modality for cancer treatment Oxygen molecules in the metastable singlet delta state O are believed to be the species that destroys cancerous cells during PDT Despite the benefit of targeted PDT that kills tumors selectively with minimum effect on surrounding healthy tissues at the present time it is difficult if not impossible to predict the res ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. The Oaks A Mobile Exercise and Education Program for People with Osteoarthritis of the Knee

    SBC: BLUE MARBLE REHAB INC.            Topic: NIA

    Project Summary This Fast Track SBIR project long term objective is to develop and test of a minimum viable product MVP of The Oaks a perioperative digital education assessment and guided exercise software application for adults with osteoarthritis of the knee KOA awaiting total knee replacement TKR surgery This product is relevant to the mission of the NIA because it addresses the call ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Development of live attenuated respiratory syncytial virus vaccines with novel thermal stable fusion protein

    SBC: Meissa Vaccines Inc            Topic: NIAID

    Respiratory syncytial virus RSV can cause lower respiratory illness LRI in otherwise healthy children and developing an effective prophylactic vaccine to mitigate RSV disease in infants is a public and global health priority according to the World Health Organization The overall goal of this project is to develop a safe and efficacious RSV vaccine for immunizing sero negative months to ye ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Inspiration Point A Digital Pulmonary Rehabilitation Tool for use with Self Management Interventions

    SBC: BLUE MARBLE REHAB INC.            Topic: NHLBI

    Project Summary The broad long term objective of this Fast Track proposal is to develop an innovative self management intervention SMI technology Inspiration Point for the treatment and study of Chronic Obstructive Pulmonary Disease COPD This application directly addresses the NHLBI SBIR requests for proposals for the development of innovative technologies for COPD the development of techn ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Noninvasive urinary monitoring of NASH by activity based nanosensors

    SBC: Glympse Bio, Inc.            Topic: 300

    Project Summary Abstract Nonalcoholic steatohepatitis NASH is dubbed the stealth epidemic and in the U S alone percent of the million people who are estimated to have NASH will progress and develop life threatening conditions including fibrosis cirrhosis hepatocellular carcinoma and liver failure By the year NASH is projected to be the leading indication for liver transplanta ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Development and validation of a novel D human in vitro model of nonalcoholic steatohepatitis to be used for novel therapeutic screening and research on disease mechanism

    SBC: Organovo, Inc.            Topic: 365

    ABSTRACT Nonalcoholic fatty liver disease NAFLD is a chronic condition that originates as lipid accumulation within hepatocytes steatosis and progresses into nonalcoholic steatohepatitis NASH characterized by lipid accumulation inflammation oxidative stress and fibrosis An estimated million adults across the U S are thought to have NAFLD with up to million more estimated to hav ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. STTR Phase I: Rational design of highly sensitive and selective chemical sensors using structural color

    SBC: DrinkSavvy, Inc.            Topic: BT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be the development of sensor-embedded "smart" drinkware (i.e., stirrers, straws and cups) to actively alert consumers prior to consumption of a "spiked" beverage, and thus provide a proactive way to prevent drug-facilitated sexual assault. This sensor technology is based on "smart" molecularly im ...

    STTR Phase I 2018 National Science Foundation
  8. STTR Phase II: An On-Demand, Computational and Microfluidic-Driven Cell-Free Protein Engineering Platform

    SBC: SYNVITROBIO INC            Topic: BT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) will be to develop a platform to accelerate the engineering of biological products, including enzymes and pathways, for production of chemicals, additives, and therapeutics. Enzymes are used in household materials (detergents and cleaners) and in chemical processes (cheese production, and bioremediation of wa ...

    STTR Phase II 2018 National Science Foundation
  9. STTR Phase II: Autonomous Landing of Small Unmanned Aircraft Systems onto Moving Platforms

    SBC: Planck Aerosystems, Inc.            Topic: EW

    The broader impact/commercial potential of this project will enable Unmanned Aerial Systems (UAS or drones) to safely and reliably operate from moving vehicles and moving vessels at sea. There is an immediate need for this capability in many industries. In commercial fishing, drones will replace manned aircraft for fish-finding operations, radically reducing cost and risk. In maritime security, dr ...

    STTR Phase II 2018 National Science Foundation
  10. STTR Phase II: Nanostraw-mediated Immune Cell Reprogramming

    SBC: Navan Technologies, Inc.            Topic: BT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project will be to develop a new tool to safely and nondestructively deliver genes and other materials into large numbers cells at the same time. New forms of therapies for cancer and other intractable diseases take advantage of a patient's own cells, re-engineered in the laboratory to target a tumor ...

    STTR Phase II 2018 National Science Foundation

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