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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development Of Novel Diabetes Therapies Based On Neutralizing FSTL3 Activity

    SBC: Fairbanks Pharmaceuticals Inc            Topic: 200

    DESCRIPTION provided by applicant Both type and type diabetes involve loss of insulin producing pancreatic cells resulting in inadequate insulin secretion to control blood glucose Eventually daily injections of insulin are required to avoid the constellation of pathologies that arise from hyperglycemia While transplantation of cadaveric pancreatic islets that contain cells has been s ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Optimizing Technology and Treatment for Non Specific Chronic Low Back Pain

    SBC: HIGHLAND INSTRUMENTS INC            Topic: N

    Proprietary This proposal includes trade secrets and other proprietary or confidential information of Highland Instruments and is being provided for use by the National Institutes of Health NIH for the sole purpose of evaluating this SBIR proposal No other rights are conferred This proposal and the trade secrets and other proprietary or confidential information contained herein shall further ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Development of immuno-PET agents for the selective imaging of CD8 T cells

    SBC: Agenus Inc.            Topic: 102

    Project summary Therapeutic strategies that seek to stimulate adaptive immunity for the treatment of cancer have recently shown convincing clinical efficacy Immune checkpoint inhibitors CPIs for example reactivate a patient s own T cells to eliminate tumors by blocking interactions that cause tumor infiltrating lymphocytes TILs to become exhausted CPIs have demonstrated remarkable success ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Precision Quality Check of Immunotherapeutics via Single Cell Cytokine Mapping

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    Despite the demonstrated benefit of CD targeted CAR T immunotherapeutics two challenges remain to bringing the therapeutics to market The first key challenge is to reproducibly manufacture the therapy so that the cellsandapos cytokine mediated function acts in a predictably consistent fashion post manufacturing The second key challenge is to manage the cellandapos s adverse effect immuno to ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. SBIR Phase II: A New Approach to Developing a Heat-stable Rotavirus Vaccine

    SBC: VAXESS TECHNOLOGIES INC            Topic: BM

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to increase global access to vaccines and reduce mortality associated with infectious diseases. As an example, Rotavirus is a major cause of severe gastroenteritis among young children and lack of vaccination results in 450,000 deaths annually. A thermostable rotavirus vaccine would c ...

    SBIR Phase II 2016 National Science Foundation
  6. Cancer Imaging and Therapy Platform

    SBC: BIOINVISION INC            Topic: 102

    Summary We will create a preclinical quantitative Cancer Imaging and Therapy Platform CITP which will allow one to study cancer biology and optimize pipelines of technologies imaging agents imaging methods targeted nano therapeutics tumor models etc especially for metastatic and invasive cancers Today primary tumor mass es are clinically controlled with surgical drug and radiatio ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A system of tools to promote development, communication, and education of off-label medication use policy

    SBC: Vasanta Health Science LLC            Topic: FDA

    Project Summary Abstract Pharmacy and Therapeutic Pandamp T Committees within healthcare organizations are challenged in developing off label use policies for two main reasons Examples of effective internal policies that have been developed at other organizations are generally not available for guidance and little evidence based research has been done on factors that lead to optimized of ...

    SBIR Phase I 2016 Department of Health and Human ServicesFood and Drug Administration
  8. Marijuana Breath Analyzer

    SBC: GINER INC            Topic: NIDA

    PROJECT SUMMARY ABSTRACT Marijuana Breath Analyzer Enforcement of drugged driving laws has attracted significant attention due to increase in drug related incidents and the decriminalization and legalization of marijuana in some states Studies have shown that marijuana use can impair a driverandapos s judgment Next to alcohol marijuana is the second most frequently found substance in the bodie ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Compact LWIR LIDAR for Aircraft Survivability

    SBC: PHYSICAL SCIENCES INC.            Topic: A15037

    Physical Sciences Inc. and Q-Peak Inc. propose to develop and demonstrate a compact, LWIR Lidar based on a state-of-the art LWIR laser transmitter to supplement aircraft survivability equipment. A Lidar operating in the LWIR provides new capability in terms of ranging and tracking next generation surface-to-air missiles at enhanced ranges. In the Phase I program, the team developed a systems archi ...

    SBIR Phase II 2016 Department of DefenseArmy
  10. SBIR Phase II: A Novel Metal-Organic Framework Material for the Separation and Recovery of Unprocessed Natural Gas During Oil and Gas Production

    SBC: FRAMERGY INC            Topic: CT

    The broader impact/commercial potential of this Small Business Innovation Research Phase II project is to provide a usable stranded and associated gas collection capacity for oil & gas exploration companies. During drilling operations, valuable gas is lost through intentional venting and flaring, causing losses in natural gas delivered to the power plant or city gate. With the sector's expansion i ...

    SBIR Phase II 2016 National Science Foundation
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