Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to provide epileptic patients, and their caregivers a smart system that can predict seizures before they occur.There are more than 3 million adults and 1 million children in the US, and more than 50 million people worldwide, suffering from epilepsy.Repeated and unpredictable seizures signif ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to improve access to vision care and eyeglasses for all Americans through a self-serve, rapid vision exam kiosk for retail stores and public spaces. An estimated 175 million Americans suffer from blurry vision, of which 30 million live without eyeglasses. By partnering with retailers, phar ...

The broader impact of this Small Business Innovation Research (SBIR) Phase II project is the advancement of sustainable and ethically produced meat alternatives. Most people have tried or know someone who has tried plant-based meats. Opinions vary but most people acknowledge that meats made from animals are not accurately recreated using plants, especially for unprocessed whole cuts like chicken b ...

PROJECT SUMMARY/ABSTRACT The MYC family proteins are comprised of three paralogs termed c-myc, N-myc, and L-myc. The MYC proteins play a fundamental role in cell proliferation and oncogenesis by regulating cellular processes such as gene transcription, protein translation, cell cycle progression, and cell death. While N-myc and L-myc drive oncogenesis in a small number of cancer types, the require ...

ABSTRACT Pulmonary arterial hypertension (PAH) is a fatal disease (without curative therapies) that is critically influenced by dysregulated inflammatory pathways. This A1 R42 Fast Track STTR application focuses on eNAMPT (extra- cellular nicotinamide phosphoribosyltransferase) as a novel, highly attractive PAH target. Aqualung Therapeutics has developed a humanized eNAMPT-neutralizing mAb, ALT-10 ...

The objective of this VAS rangefinder Phase I SBIR effort is to complete key enabling trade studies which will inform the development of the range finder through a Phase II effort. The resulting VAS rangefinder will be a low-cost, easy-to-use device that is capable of operating 24/7 in urban or near-urban environments with ambient light sources.

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project addresses the societal need for a non-thermal, economical, and efficient solution for sterilizing deadly pathogens that are common in medical facilities and everyday living spaces. The commercial opportunity lies in developing a non-thermal, portable, safe, and economical sterilization device ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is focused on developing an energy storage technology that stores electricity as heat and converts its back to electricity whenever needed using thermophotovoltaics (TPV). If successful, the innovation will help transition the United States (US) towards a fully renewable electrical grid. The c ...

The broader/commercial impact of this Small Business Innovation Research (SBIR) Phase II project is accelerating the manufacturing of and access to newly developed therapeutics and vaccines. To address global health problems, effective and safe new biologics such as therapeutics and vaccines will need to be manufactured at unprecedented large scales and short times. Accelerating access to new biol ...

This Small Business Innovation Research (SBIR) Phase II project develops a cow's milk testing system using mobile spectroscopy and machine learning to provide rapid and automatic milk testing. The team aims to address the annual $32 billion global loss from bovine mastitis, an udder disease, due to the lack of farm-level early detection technology. The project helps farmers detect mastitis early, ...