Award Data

DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the development of a novel, bioactive polymer for use in ventricular assist devices (VAD), and other long-term blood contacting implantable devices. Although VADs are becoming an important therapeutic option for patients in heart failure, serious problems persist secondary to thromboembolic complications and continue t ...

DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the commercialization of a pediatric ventricular assist device (VAD). Although, VADs, both implantable and paracorporeal, have become an important surgical option for adult patients with myocardial failure unresponsive to less aggressive therapy, no VADs are commercially available for short-term use in children or smal ...

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This SBIR Phase II research project strives to develop an Advanced Ultrasonic Beamformer that is unparalleled in its scalability and signal processing features. The ultrasonic beamformer architecture will be unique in its breadth of features. The architecture was developed as the superset of features across several fields including medical imaging, medical therapy, bone density measurement, vascul ...

The Future Combat System (FCS) military diesel engine propulsion systems tribological considerations are predicted to be compromised primarily by the temperature capability of the lubricating fluid. Thermal oxidation resulting in lubricant work in rigidcondition breakdown and formation of deposits are typical causes of engine failure at high temperature operating conditions. Work in the Phase I ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Although weight loss is the most effective treatment for type 2 diabetes, current methods for reducing weight typically are insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop and license novel the ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Existing drug and dietary treatments for obesity are only modestly effective. An approach that is very likely to be effective in treating obesity and with a good side effect profile is a drug that acts directly on lipid metabolism in the fat ...

A compact, reliable, efficient and inexpensive cryocooler requiring less than 1 kW of power for 2W of cooling at 10 Kelvin is being developed and will be demonstrated. This performance is at least twice as efficient as the best current state-of-the-artfor small low-temperature cryocoolers. The proposed technical approach, whose technical feasibility and suitability for space-based applications h ...

Due to environmental control requirements, the sources of advanced separator materials for existing Ni-H2 batteries are going out of business. We are proposing to develop a cost-competitive, high-performance battery separator that can replace the currentNi-H2 separators without major cell design/assembly changes. We are planning to develop an environmentally benign battery separator and demonstrat ...

70570B02-II Currently available Li-ion batteries do not meet Department of Energy targets for electric vehicle (EV) or hybrid electric vehicle (HEV) applications. The problem is that today¿s cathode materials do not allow the specific energy and power density targets to be achieved while simultaneously being low cost, safe under abusive conditions, and environmentally benign. This project w ...