Award Data

Location GWATHMEY, INC. 763 E CONCORD AVE CAMBRIDGE, MA 02138 United States 2R44HL068354-02A2 $3 900 210.00 2 008 Optimization of Iron Chelator Delivery System Department of Health and Human Services National Institutes of Health SBIR Y N Y PHS2007-2 GWAT ...

DESCRIPTION (provided by applicant): Ischemic ventricular tachycardia (VT) is a contributing cause to more than half of the 300,000 sudden cardiac deaths that occur annually in the United States. Implantable cardioverter defibrillators (ICDs) are the stand ard therapy but they are expensive the total cost of an ICD implant approaches 50,000 and the United States spends more than 2.2B on these im ...

Location 100 Grove Street Suite 315 Worcester, MA 01605 United States 2R44DK059088-04 $2 892 330.00 2 008 Development and Performance Evaluation of a Handheld Noninvasive Glucose Monitor Department of Health and Human Services National Institutes of Healt ...

DESCRIPTION (provided by applicant): Diabetes remains the leading cause of non-traumatic lower extremity amputations. Most amputations are preceded by a foot ulcer, so that successfully treating, or better still preventing, foot ulcers should reduce the n umber of diabetes related amputations. The majority of foot ulcers in diabetic patients are the result of loss of protective sensation (LOPS) s ...

DESCRIPTION (provided by applicant): The Company is developing SmartInsulin(tm), which is intended to be a once-a-day, self- regulating insulin injection for the treatment of Type I diabetes. It is designed as a "drop- in" replacement product for the 4 million insulin-using diabetics in the United States. SmartInsulin is designed to provide significant benefits to insulin-dependent diabetics inclu ...

DESCRIPTION (provided by applicant): The Phase II work proposed here involves the high-throughput proteome profiling of molecules associated with cardiovascular disease. Comparative profiling of disease-relevant species will lead to a marketable product - the PPM Cardiovascular Health and Wellness Report. Molecular profiling is accomplished using novel IMS-MS instrumentation and a three-minute an ...

DESCRIPTION (provided by applicant): Human cytomegalovirus (HCMV) infections continue to represent a major health concern in the immunocompromised population, especially recipients of bone marrow and solid-organ transplants. HCMV remains an important cause of congenital viral infection associated with deafness, mental retardation and mortality. Current therapy, which includes ganciclovir (GCV), c ...

DESCRIPTION (provided by applicant): The objective of our NIAID Biodefense Phase I SBIR program was to develop, and commercialize field deployable nucleic acid analysis devices for use in biodefense applications. We have begun to sell IsoAmp II kits that will allow our clients to develop home brew assays (we list customers in the commercialization plan). For example, the LANL has obtained NIH fu ...

Location GLSYNTHESIS, INC. ONE INNOVATION DRIVE WORCESTER, MA 01605 United States 2R44AG015259-04 $1 688 750.00 2 008 Novel Drugs to Treat Urinary Incontinence Department of Health and Human Services National Institutes of Health SBIR N N N PHS2007-2 GLSy ...

DESCRIPTION (provided by applicant): Robotics has found a well accepted role in surgical procedures, particularly in laparoscopic procedures where arms can now be used with remote manipulation by a surgeon with direct visual feedback from the laparoscope t o dissect, suture, tie, and perform complex procedures in the cardiac, thoracic, and abdominal spaces. Current robotic technology, however, is ...