Award Data

DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the development of a novel, bioactive polymer for use in ventricular assist devices (VAD), and other long-term blood contacting implantable devices. Although VADs are becoming an important therapeutic option for patients in heart failure, serious problems persist secondary to thromboembolic complications and continue t ...

DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the commercialization of a pediatric ventricular assist device (VAD). Although, VADs, both implantable and paracorporeal, have become an important surgical option for adult patients with myocardial failure unresponsive to less aggressive therapy, no VADs are commercially available for short-term use in children or smal ...

This SBIR Phase II research project strives to develop an Advanced Ultrasonic Beamformer that is unparalleled in its scalability and signal processing features. The ultrasonic beamformer architecture will be unique in its breadth of features. The architecture was developed as the superset of features across several fields including medical imaging, medical therapy, bone density measurement, vascul ...

This Small Business Innovative Research Phase I project builds on a research program investigating the design of process-based software development tools and methodologies. The project will develop a next generation of this software that supports the creation, refinement, and adaptation of software development methodologies in a principled manner while preserving the need for rapid innovation. Th ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Although weight loss is the most effective treatment for type 2 diabetes, current methods for reducing weight typically are insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop and license novel the ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Existing drug and dietary treatments for obesity are only modestly effective. An approach that is very likely to be effective in treating obesity and with a good side effect profile is a drug that acts directly on lipid metabolism in the fat ...

R3 Logic proposes to develop an openly accessible Design Environment that will incorporate CAD tools needed for the analysis and design of 3D integrated circuits, including schematic capture, VHDL interfaces, 3D physical layout, verification, 3D parasiticextraction, interactive coupled electro-thermal simulations, and thermally-aware place and route methods. We will achieve this goal, first by bui ...

The objective of this effort is to create an innovative bioinformatics platform for microarray data management and analysis. This platform will overcome the following limitations inherent in current microarray systems: (1) current systems typically do notaddress all types of array data, (2) current systems do not record the context of the samples, which hinders scientific and statistically relevan ...

Crested multi-layer tunnel barriers have been proposed, which offer a revolutionary solution to overcome density to speed trade-offs characteristic of present data storage technologies. Practical implementation of the proposed technology will involve useof thin film materials that are readily manufacturable and CMOS-compatible. A critical need exists for experimental verification of the theoreti ...

The SAE smoke number has been an important measurement for prevention of black, sooty plumes in military and commercial aviation. The current method, however, requires the use of a complex extraction system to bring engine exhaust through a filter paper,and then requires a person to remove the soot covered filter and perform a measurement in an optical reflectometer to determine the smoke number. ...