Award Data

Proliferation of nuclear weapons is a serious threat in the world today. One way to determine the presence of nuclear weapons is to detect neutrons emitted by special nuclear material(SNM) such as highly enriched uranium and weapons grade plutonium. The purpose of this project is to develop improved solid state neutron detectors from CVD diamond for homeland security applications. Phase I work wil ...

The use and applications of radiological sources, for power, medical, and defense applications, continuously increases with time. Illicit nuclear materials represent a threat for the safety of the American citizens and the detection and interdiction of a nuclear weapon is a national problem that has not been yet solved. This represents an enormous challenge to current detection methods and monitor ...

THIS RESEARCH IS DIRECTED TOWARD THE DEVELOPMENT OF TECH- NOLOGIES AND DEVICES WHICH WILL ALLOW FOR IMPROVEMENTS IN EXERCISE AND RECREATIONAL ACTIVITIES FOR HANDICAPPED AND DISABLED INDIVIDUALS. THE SPECIFIC APPROACH IS TO COMBINE THE THERAPEUTIC VALUE OF EXISTING EXERCISE EQUIPMENT WITH THE RECRECREATIONAL, ENTERTAINMENT AND MOTIVATIONAL ATTRI- BUTES OF COMPUTER VIDEO GAMES. A CONVENTIONAL EXERCI ...

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Boston MicroSystems (BMS) proposes to develop a cell-phone sized instrument for detecting hazardous chemical and explosive threats. The instrument is based on BMS' PicoSensor® chemical and explosives detection platform, which has been developed in part under DHS support and is capable of sensing explosives and toxic chemicals at ppb and even ppt (trillion) levels. The Picoensor® consists of a ME ...

PROVIDING INDIVIDUALIZED INSTRUCTION FOR DISABLED STUDENTS IN SPECIAL EDUCATION PLACEMENTS IS A TIME-CONSUMING PROCESS FOR EDUCATORS AND THUS COSTLY. COMPUTERIZED AND INTERACTIVEVIDEODISK EDUCATIONAL FORMATS MAY NOT BE READILY CUSTOMIZED FOR THE INDIVIDUAL STUDENT. HOWEVER, COMMONLY-AVAILABLE IN PERSONAL COMPUTERS AND HAND-HELD CAMCORDERS ARE TOOLS AVAIL ABLE IN MOST SCHOOLS. IF A PERSONAL COMPUTE ...

Ion mobility spectrometer based explosives trace detectors (ETD) have been widely used in airport check points, ports of entry, government buildings, and other high security facilities. Most of these systems require manual collection of trace particles from vehicles via direct swabbing of surface areas of interest. Sample collection efficiency and inconsistency pose significant challenges to the e ...

DESCRIPTION (provided by applicant): An electrospray ionization ion mobility spectrometer (ESI-IMS) is proposed to be used as an innovative process analytical technology (PAT) to overcome the limitations of current cleaning validation systems for pharmaceu tical manufacturing and quality assurance. With its sensitivity, speed and portability, IMS has already been used in trace chemical detection t ...

This Phase I project develops a prototype FluidMath software application and demonstrates its feasibility as an intervention in the teaching and learning of basic algebra. At its core, the prototype includes a first of its kind recognition engine which enables a Tablet PC to interpret mathematical expressions written on its screen with an electronic stylus. In addition, the prototype will include ...

DESCRIPTION (provided by applicant): Liver toxicity is the leading cause of pre-launch and post-market attrition of pharmaceutical compounds (i.e. Rezulin, Prexige). Significant species-specific differences in organ functions now necessitate supplementatio n of animal data with assays designed to assess human responses to drugs. Adherent cultures of primary human hepatocytes are considered to be t ...