Award Data

Improved head and hearing protection is required for aircraft maintainers working on a carrier flight deck during launch and recovery operations. Legacy Flight Deck Cranials are inadequate in many aspects including hearing protection, impact protection, cleaning, comfort, and compatibility with night vision devices (NVDs) and with chemical, biological, and radiological (CBR) equipment. In this p ...

Location GWATHMEY, INC. 763 E CONCORD AVE CAMBRIDGE, MA 02138 United States 2R44HL068354-02A2 $3 900 210.00 2 008 Optimization of Iron Chelator Delivery System Department of Health and Human Services National Institutes of Health SBIR Y N Y PHS2007-2 GWAT ...

DESCRIPTION (provided by applicant): Ischemic ventricular tachycardia (VT) is a contributing cause to more than half of the 300,000 sudden cardiac deaths that occur annually in the United States. Implantable cardioverter defibrillators (ICDs) are the stand ard therapy but they are expensive the total cost of an ICD implant approaches 50,000 and the United States spends more than 2.2B on these im ...

The goal of this project is to design, build, and test an active electromagnetic induction (EMI) sensor array for detecting and characterizing IEDs. At low frequencies (below a few kHz), an EMI sensor is a magnetometer that primarily responds to susceptibility targets (i.e., ferrous objects). The main difference is that, while a magnetometer uses the earth’s field as the illuminating source, an ...

Orbital Research Inc. proposes to design and develop an innovative, low-cost Miniature Control Actuator System (MCAS) for active aerodynamic control of Army's next-generation smart munitions. The MCAS will employ miniature flow control actuators and advanced control strategies to provide in-flight course-correction capability for Army’s line-of-sight (LOS) and beyond line-of-sight (BLOS) munitio ...

Location 100 Grove Street Suite 315 Worcester, MA 01605 United States 2R44DK059088-04 $2 892 330.00 2 008 Development and Performance Evaluation of a Handheld Noninvasive Glucose Monitor Department of Health and Human Services National Institutes of Healt ...

The current use of polymer matrix composite materials aboard U.S. Navy ships has been limited to mainly exterior parts such as DDX topside structures, sonar bow domes, towed array fairings, diving planes, control surfaces and the prototype submarine sail dome for VA class submarines. There has been increasing interest in the development of composite materials for applications inside ships and sub ...

DESCRIPTION (provided by applicant): This proposal intends to advance the regional delivery of a chimeric adeno-associated virus (rAAV)-based, highly-truncated dystrophin (minidystrophin) gene therapy for the treatment of Duchenes Muscular Dystrophy (DMD). Experiments focus on completing preclinical studies required to initiate, the also proposed, FDA recommended Phase Ib bridging study. The prop ...

DESCRIPTION (provided by applicant): Traumatic brain injury (TBI), principally as a result of impaction on the intact closed skull, occurs in vehicular incidents, falls, acts of violence, and sports accidents. TBI is the leading cause of death and disability in the United States, with an annual incidence rate of 1.5 million. Of these, 50,000 die acutely, over 230,000 are hospitalized, and 80,000 ...

DESCRIPTION (provided by applicant): The Company is developing SmartInsulin(tm), which is intended to be a once-a-day, self- regulating insulin injection for the treatment of Type I diabetes. It is designed as a "drop- in" replacement product for the 4 million insulin-using diabetics in the United States. SmartInsulin is designed to provide significant benefits to insulin-dependent diabetics inclu ...