Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Develop predictive human cardiomyocyte-based all optical assay for cardiotoxicity

    SBC: Q-state Biosciences, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Develop predictive human cardiomyocyte based all optical assay for cardiotoxicity Cardiotoxicity is the leading cause of safety driven withdrawal a all stages and limitation of drug compounds The current cardiac safety paradigm nonclinical guidance ICH S B focuses on in vitro hERG assays which prove to be suboptimal in predicting a compoundandapos s cardioto ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Stem Cell Bioreactor for Cardiac Care

    SBC: Sentien Biotechnologies, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant The goal of this Fast Track Phase I II SBIR is to test a novel extracorporeal system for delivering mesenchymal stem cell MSC secretions to treat acute myocardial infarction MI We will use the Sentien proprietary extracorporeal delivery system to treat swine subjected to a clinically relevant model of MI The project specific aims are Simulated blood ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. FAST TRACK: IND Enabling Studies for Oral Cancer

    SBC: PRIVO TECHNOLOGIES, LLC            Topic: 102

    DESCRIPTION provided by applicant According to the Oral Cancer OC Foundation oral and pharyngeal cancer will cause deaths this year in the US killing roughly one person per hour Currently cisplatin CIS is at the forefront of platinum based chemotherapeutics for treating OC However its efficacy is often hindered by its significant systemic toxicity as a resut of traditional bolus ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Zinc Coatings on Steel by Cermacladtm to Replace Galvanizing Pickling Lines

    SBC: MesoCoat            Topic: 13NCERB1

    Every year, a significant amount of money is lost due to atmospheric attack of steel parts. A convenient and effective way for corrosion protection is coating the unalloyed steel with a thin layer of zinc (Zn) metal by galvanizing. Pickling is an essential step of this process to ensure high quality surface of steel for further processing. In this process, acid is used to remove scale from the su ...

    SBIR Phase II 2015 Environmental Protection Agency
  5. High Flux Nanofiltration Membrane for Emerging Contaminant Control

    SBC: ASPEN PRODUCTS GROUP, INC.            Topic: 13NCERA1

    A variety of organic and inorganic contaminants originating from municipal, agricultural, and industrial wastewater sources are being found at increasing frequency in the Nation’s natural and drinking water supplies. These “emerging contaminants” include pharmaceuticals, antibiotics, steroids/hormones, flame retardants, perfluorinated compounds, personal care products, and herbicides/pestici ...

    SBIR Phase II 2015 Environmental Protection Agency
  6. Contamination and Lasting Effects Analysis for Negative Substances and Elements (CLEANSE)

    SBC: Charles River Analytics, Inc.            Topic: A13078

    Environmental awareness has become an increasingly important issue for military training facilities. Given the nature of military training activities, it is crucial for training facility managers to understand the relationships among repeated contaminant release, contaminant migration, and available mitigation techniques. Current technologies used to assess the impact of contaminants do not consid ...

    SBIR Phase II 2015 Department of DefenseArmy
  7. Pathogen Specific Antimicrobial Coatings For Fabrics

    SBC: Giner, Inc.            Topic: A14AT012

    Antimicrobial treatment of military textile systems is intended to provide enhanced protection to the Warfighter in the field by preventing colonization of harmful bacteria that cause problems such as odor, dermatitis, impetigo, cellulitis, and other skin irritations. Current treatments can impart antimicrobial functionality to textiles; however, they all possess broad-spectrum antimicrobial activ ...

    STTR Phase II 2015 Department of DefenseArmy
  8. Predictive High-Fidelity Modeling Capability for High-Brightness Photoinjectors

    SBC: Gnosys Systems Inc.            Topic: 06a

    "High brightness and high average power Free Electron Lasers known as x-ray FELs, developed by DOE, are intently desired by the scientific community for their unique capabilities and for the opportunities they enable in the medical and biological sciences, such as imaging biological molecules or chemical reactions. Beam optics codes (particularly Particle-in-Cell codes) couple non-uniformity and s ...

    STTR Phase II 2015 Department of Energy
  9. Innovative Motion Measurement Package (M2P) for Guided and Un-Guided Munitions

    SBC: ORBITAL RESEARCH INC            Topic: A152092

    Current and future munitions will require innovative sensor packages to accurately measure and estimate their motion during and after gun launch. This technology must be low Size, Weight and Power to fit within guided/unguided munitions. Orbital Research will leverage its extensive experience in the development of gun-hardened electronics to develop an innovative Motion-Measurement-Package (M2P) t ...

    SBIR Phase I 2015 Department of DefenseArmy
  10. Category-Theoretic Tool for Manufacturing-related Information Integration

    SBC: CATEGORICAL INFORMATICS, INC.            Topic: 9010173R

    Categorical theory has recently been successfully applied to translate information from one computer system to another. Researchers at MIT have developed a prototype software tool based on category theory for solving information-integration programs. The tool has successfully solved small-scale information-integration problems including a problem identified by NIST about enriching the manufacturin ...

    SBIR Phase I 2015 Department of CommerceNational Institute of Standards and Technology
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