Award Data

THE OBJECTIVE OF THIS PROGRAM IS TO DESIGN AND BUILD A STAPLER FOR PERFORMING END-TO-END AND END-TO-SIDE ANASTOMOSES ON MEDIUM TO LARGE VESSELS, AND FOR REPAIRING BLOOD VESSELS AND VASCULAR ANEURYSMS, AND TO DEVELOP A SURGICAL PROTOCOL FOR ITS USE. THE METHOD PROPOSED USES A SPECIAL STAPLER AND CONFIGURATION OF STAPLES WHICH MINIMIZESBLOOD CONTACT WITH THE STAPLES, DOES NOT RESTRICT THE FLOW OF BL ...

DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the development of a novel, bioactive polymer for use in ventricular assist devices (VAD), and other long-term blood contacting implantable devices. Although VADs are becoming an important therapeutic option for patients in heart failure, serious problems persist secondary to thromboembolic complications and continue t ...

DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the commercialization of a pediatric ventricular assist device (VAD). Although, VADs, both implantable and paracorporeal, have become an important surgical option for adult patients with myocardial failure unresponsive to less aggressive therapy, no VADs are commercially available for short-term use in children or smal ...

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THE PROPOSED WORK INVOLVES APPLICATION OF SUPPORTED MOLTEN SALT CATALYSIS TO THE CATALYTIC ENDOTHERMIC DEHYDROGENATION OF HIGH ENERGY-DENSITY AVIATION FUELS. THE CATALYSTS OF INTEREST ARE HETEROGENEOUSLY DISPERSED PLATINUM AND NICKEL, TO BE USED ALONE OR IN BIMETALLIC CLUSTERS. THE MOLTEN SALTS TO BE USED INCLUDE BINARY AND TERNARY EUTECTICS INVOLVING ALKALI METAL CHLORIDES AND HYDROXIDES. THE SUP ...

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This SBIR Phase II research project strives to develop an Advanced Ultrasonic Beamformer that is unparalleled in its scalability and signal processing features. The ultrasonic beamformer architecture will be unique in its breadth of features. The architecture was developed as the superset of features across several fields including medical imaging, medical therapy, bone density measurement, vascul ...

INNOVATIVE APPROACHES ARE DESCRIBED IN THIS PROPOSAL FOR SUPPRESSING FREQUENCY MODULATION ON A SINUSOIDAL CARRIER. PARTICULAR EMPHASIS IS DIRECTED TO THE SUPPRESSION OF IDENTIFIABLE COMPONENTS OF A COMPOSITE MODULATION PROCESS FOR THE PURPOSE OF RETAINING, FOR SEPARATE MEASUREMENT, ANY FORM OF RANGE-RATE DOPPLER SHIFT/MODULATION PRESENT. THE PROPOSED EFFORT WILL CONSIST OF AN ANALYTICAL STUDY FOR ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Although weight loss is the most effective treatment for type 2 diabetes, current methods for reducing weight typically are insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop and license novel the ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Existing drug and dietary treatments for obesity are only modestly effective. An approach that is very likely to be effective in treating obesity and with a good side effect profile is a drug that acts directly on lipid metabolism in the fat ...