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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Expanding Access to Electronic Property Modeling in Scintillator Crystal Growth and Development

    SBC: Radiation Monitoring Devices, Inc.            Topic: 03a

    The development of radiation detection materials would benefit with greater access to computational models that relate physical traits seen in manufacture with complex energy transitions occurring in the material that control operating performance. However, the HPC requirements behind these models remain beyond the reach of most businesses involved in this small yet vital field impacting National ...

    STTR Phase I 2018 Department of Energy
  2. Supercritical Treatment Technology for Water Purification

    SBC: ENVERGEX LLC            Topic: 20a

    Wastewater from oil and gas production has high total dissolved solids (TDS) and organics and needs to be treated for safe disposal or reuse. Coal-fired power plant discharges and mining effluents share similar high TDS and organic contents. This project targets the development of an energy efficient, and robust supercritical desalination technology to treat hypersaline solutions, destroying organ ...

    STTR Phase I 2018 Department of Energy
  3. An Analytical Technology Platform to Identify Symbiotic Interactions Between PGPR and Root Microbiome Members from Biofuel Feedstocks

    SBC: Powers & Zahr, LLC            Topic: 22a

    The overall goal of this STTR proposal is to establish a commercial microwell technology for high-throughput screening and characterization of interactions that are critical to plant growth promoting rhizobacteria (PGPR) survival and function. PGPR can be used to improve crop stress tolerance by enhancing root function; providing nutrient uptake, nitrogen fixation, hormone regulation, and suppress ...

    STTR Phase I 2018 Department of Energy
  4. A Novel Cold Spray Method for Repair and Mitigation of Cracks in Spent Nuclear Fuel Storage Canisters

    SBC: HAMR Industries LLC            Topic: 31a

    Dry storage of spent nuclear fuel (SNF) is canisters can be threatened by corrosion of the metallic canisters which incur substantial repair and replacement costs and logistical issues. A novel cold spray repair and mitigation approach is proposed to repair corroded SNF canisters and mitigate the corrosion threat for fabricated canisters. The proposed work utilizes a novel cold spray technique whe ...

    STTR Phase I 2018 Department of Energy
  5. High Power Ceramic Disk Lasers with Gradient Doping Made by Direct Ink Writing

    SBC: Radiation Monitoring Devices, Inc.            Topic: 25c

    The power output of the high power lasers used in physics research is limited by the materials available for making the gain media in the laser. Future increases in power will require new and better materials. Operation at high power creates great thermal stresses that can lead to effects such as birefringence, thermal lensing or even physical fracture damage to the host itself. Effective cooling ...

    STTR Phase I 2018 Department of Energy
  6. Discovery of Zika virus therapeutics using a replicon assay

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    ABSTRACT The Zika virusZIKVis the cause of an explosive pandemic of infections across South and Central Americathe Caribbeanand the southeastern region of the United StatesZIKV is a flavivirusa family of small positive strand RNA viruses that includes Dengue virusDENVWest Nile virusWNVYellow fever virusYFVand hepatitis C virusHCVZIKV is transmitted to humans by mosquitoes of the Aedes genusFor the ...

    STTR Phase I 2018 Department of Health and Human Services
  7. Intravascular molecular-structural NIRF-IVUS imaging of coronary artery disease

    SBC: IntraVascular Imaging, Inc.            Topic: NHLBI

    The goal of this Phase I STTR project is to constructoptimizeand test a clinically viable intravascular near infrared fluorescence intravascular ultrasoundNIRF IVUSimaging catheter for simultaneous molecular and structural diagnosis of coronary artery diseaseCADCAD is a worldwide leading cause of death and disabilityincluding acute myocardial infarctioncongestive heart failureand sudden cardiac de ...

    STTR Phase I 2018 Department of Health and Human Services
  8. Advancing a novel portable detection method for cannabis intoxication

    SBC: Brain Solutions, LLC            Topic: NIDA

    Intoxication from marijuanaMJimpairs psychomotor performance and at least doubles the risk of motor vehicle accidentsThe ongoing wave of legalization of MJ has brought increasing prevalence of driving while intoxicated with MJHoweverthere is no quantitative biologic test that can accurately determine whether an individual is acutely impaired from MJ intoxicationAssays of the primary intoxicating s ...

    STTR Phase II 2018 Department of Health and Human Services
  9. Exploration of Low-Cost Long-Timescale Free Energy Perturbations on FPGAs

    SBC: Silicon Insite, Inc.            Topic: 400

    Drug discovery is challenging and expensiveespecially in the phase of lead optimization whichpredicts binding to a targetComputational approaches can add substantial valueComputingrelative binding free energiesRBFEbetween congeneric molecules using molecular dynamicsMDgreatly reduces the search space and considerably improves convergenceThe Silicon TherapeuticsSTXINSITE platform uses an RBFE proto ...

    STTR Phase I 2018 Department of Health and Human Services
  10. MDCT Quantification of hepatic tumor viability for assessment of cancer therapy

    SBC: IQ Medical Imaging LLC            Topic: 102

    Project SummaryAbstract Tumor imaging quantification is critical for diagnosisstagingand treatment evaluationand multi detector CTMDCTis the clinical imaging modality commonly used for patients diagnosed with hepatic malignancy because of its relatively low cost and wide availabilityConventional tumor quantification using either linear or volumetric measurement has demonstrated significant limitat ...

    STTR Phase II 2018 Department of Health and Human Services

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