Award Data

DESCRIPTION (provided by applicant): In this proposal we respond to the call by the National Institute of Environmental Health Sciences (NIEHS) in the PHS 2007-2 Omnibus Solicitation for new products/devices, tools, assays to improve our ability to precis ely measure environmental exposures to individuals with high temporal and spatial resolution. According to the solicitation, the device should ...

DESCRIPTION (provided by applicant): Iodine deficiency disorder (IDD) has been identified by the World Health Organization as a serious global health problem affecting 740 million people in 130 countries. Iodine deficiency is the most common cause of preventable brain damage, with nearly 50 million people suffering some degree of IDD-related brain damage. IDD is preventable and treatable by iodiza ...

DESCRIPTION (provided by applicant): The ultimate objective of this proposed program is the commercialization of a universal transcutaneous energy transfer (TET) system with a high performance implantable battery. This integrated power system will be adapt able to a host of next generation fully implantable mechanical circulatory support (MCS) systems. To date, fully implantable systems (i.e. the ...

DESCRIPTION (provided by applicant): WAYFINDER: A Cognitive Aid for Independent Transportation ABSTRACT Transportation and mobility have long been areas of great dependency for individuals with intellectual disabilities, such as mental retardation. Few individuals with intellectual disabilities obtain drivers licenses. Other typical modes of transit, such as taxi service, are prohibitive due to co ...

An estimated 25% of primary care patients may have some form of substance abuse. The goal of this project is to develop web-based educational and performance support tools for primary care providers (PCPs) to engage in substance abuse screening, brief intervention, referral, and treatment (SBIRT). The effort will be grounded in an integrative reasoned action approach to provider performance, incor ...

DESCRIPTION (provided by applicant): Ischemic ventricular tachycardia (VT) is a contributing cause to more than half of the 300,000 sudden cardiac deaths that occur annually in the United States. Implantable cardioverter defibrillators (ICDs) are the stand ard therapy but they are expensive the total cost of an ICD implant approaches 50,000 and the United States spends more than 2.2B on these im ...

DESCRIPTION (provided by applicant): New upper-extremity assistive appliances coming into the orthotics and prosthetics (OandP) market are increasingly technologically sophisticated and expensive, which has given rise to a growing population of amputees w ho cannot obtain them or make use of them for various reasons and thereby enjoy no benefit. Current estimates put the number of upper-extremity ...

DESCRIPTION (provided by applicant): Owing to certain intrinsic advantages of conventional or cable-operated assistive appliances, many upper- extremity amputees prefer using simple voluntary opening (VO) split hook terminal devices for some tasks. Ampute es who regularly contribute their time and expertise helping ADA develop innovative new assistive appliances continue to request the company cr ...

DESCRIPTION (provided by applicant): Cancer treatment today is in need of tumor-specific and effective therapies that do not harm the patient and thereby compromise treatment efficacy and prolong recovery time. A multi-modal therapeutic and imaging agent t hat does not damage healthy living tissue would have tremendous benefit to researchers and victims of this deadly disease. Nanomaterials have t ...

Cancer biomarker detection and cancer proteomics and genomics research require analysis platforms that provide high sensitivity and high throughput. In phase I, we will develop a novel nano-enabled sensing platform that is based on metal nanopillar patterned surface on a continuous Au thin film. This platform provides dramatic sensitivity increase through the combination of fluorescent enhancement ...