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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 5815 results
  1. Clinical and Immunologic Evaluation of ProstAtak for Prostate Cancer

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this project is to develop a new therapeutic to improve the outcome for patients with intermediate-risk prostate cancer. The indication is a first-line adjuvant to be combined with radiation therapy for prostate cancer. The desired outcomes are improved local control rate, decreased recurrence and improved disease-free survival. This grant ...

    SBIR Phase II 2009 Department of Health and Human Services
  2. Developing Novel Antibiotics Against Yersinia pestis

    SBC: NOVOBIOTIC PHARMACEUTICALS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop broad-spectrum antibiotics against Yersinia pestis and other important human pathogens. The potential use of engineered, multi-drug-resistant strains as agents of bioterrorism necessitates the development of new anti-Y. pestis therapies. This is a challenging goal, since the last novel class of broad-spectrum antib ...

    SBIR Phase II 2006 Department of Health and Human Services
  3. Microfluidic DNA Sequencing

    SBC: GNUBIO, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): This is a Phase II SBIR proposal to increase the throughput of our DNA sequencing instrument to enable whole genome sequencing with high efficiency and accuracy for a cost of under 1000 per genome. In Phase I, we developed a working sequencing assay, a microfluidic platform and camera system, and analysis methodology that enable genome alignment and variant ca ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Rapid Clinical Surge-Testing for Biothreat Agents

    SBC: FIRST LIGHT BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Following a bioterrorist attack, hundreds of thousands of potential victims may require testing and treatment. The critical need to test large numbers of people for exposure to a biothreat agent may overwhelm the capacity of the clinical and public health infrastructure. The approximately 25,000 sentinel laboratories in the Laboratory Response Network, which co ...

    SBIR Phase II 2005 Department of Health and Human Services
  5. Optimization of Iron Chelator Delivery System

    SBC: GWATHMEY, INC.            Topic: N/A

    Location GWATHMEY, INC. 763 E CONCORD AVE CAMBRIDGE, MA 02138 United States 2R44HL068354-02A2 $3 900 210.00 2 008 Optimization of Iron Chelator Delivery System Department of Health and Human Services SBIR Y Y Y PHS2007-2 GWATHMEY, INC. Phase II Woman Owne ...

    SBIR Phase II 2008 Department of Health and Human Services
  6. Long-acting PTH for hypoparathyroidism

    SBC: Extend Biosciences Inc.            Topic: NIDDK

    Project Summary Hypoparathyroidism is a rare disease that results from a deficiency or inability to make sufficient amounts of parathyroid hormonePTHUntreated or inadequately treated hypoparathyroidism leads to clinically significant mineral related metabolic issues including hypocalcemiawhich leads to heart arrhythmiasspasms of the vocal cordsand seizuresCurrent management of the disease for the ...

    SBIR Phase II 2017 Department of Health and Human Services
  7. Bactericidal antibiotic for Vancomycin Resistant Enterococci

    SBC: Arietis Corporation            Topic: NIAID

    DESCRIPTIONprovided by applicantThe goal of the project is to develop a therapeutic against vancomycin resistant enterococcusVREThese infections are a serious health concern because antibiotic resistance has gotten to the point where there are few or no effective treatment options availableFor the enterococciresistance is inherently linked to toleranceth ability of the pathogen to survive in the p ...

    SBIR Phase II 2016 Department of Health and Human Services
  8. Novel Catheter for Treatment of Ventricular Tachycardia

    SBC: Thermedical Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Ischemic ventricular tachycardia (VT) is a contributing cause to more than half of the 300,000 sudden cardiac deaths that occur annually in the United States. Implantable cardioverter defibrillators (ICDs) are the stand ard therapy but they are expensive the total cost of an ICD implant approaches 50,000 and the United States spends more than 2.2B on these im ...

    SBIR Phase II 2008 Department of Health and Human Services
  9. RandD- MEDICAL: BIOMEDICAL (BASIC RESEARCH)

    SBC: IMMUNETICS, INC.            Topic: NHLBI

    This project is aimed at the development of an enzyme immunoassay (ELISA) for screening blood for antibodies to Babesia microti. Human babesiosis is a malaria-like illness due to infection of red blood cells by various species of protozoan parasites belonging to the genus Babesia. Most human infections reported in the United States are caused by B. microti which is endemic in parts of the northeas ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Immunoassay for diagnosis of Babesia infection

    SBC: IMMUNETICS, INC.            Topic: R

    DESCRIPTION provided by applicant In this Phase II project development and clinical validation of an ELISA test for in vitro diagnosis of Babesia microti infection will be completed Babesiosis is an emerging tick borne parasitic disease which may cause severe to fatal illness in immunocompromised or otherwise weakened patients and may be carried in the blood subclinically in up to of the ...

    SBIR Phase II 2015 Department of Health and Human Services

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