Award Data

The objective of this program is to characterize the upper atmosphere electrical environment so that the effects of this environment on high altitude airships (HAA) and other platforms intending to operate in this environment can be determined, and protection methods developed. This includes transient luminous events (TLEs), such as red sprites and blue jets and their associated electrical propert ...

Highly energetic chemical processes play a central role in many military and commercial applications. For example, spectral emissions from missile plumes, arising from high-velocity chemical interactions of exhaust gases with the atmosphere, are used to detect, track, and identify threat targets. Detailed, quantitative knowledge of the energy-dependent chemical reaction cross sections and rates i ...

Radiation Hardened Multi-color infrared (IR) focal planes are required for MDA/SMDC systems applications . Key to meeting these system requirements is to develop multi-color radiation hardened HgCdTe focal plane arrays for LWIR band ( 7-14 microns) and VLWIR band with wavelength of greater than 14 microns with high pixel uniformity, reduced readout noise, improved resolution, and higher temperatur ...

DESCRIPTION (provided by applicant): A separation method will be tested and evaluated to determine the feasibility of providing no carrier added lutetium-177 (Lu-177) for use in radiotherapeutic applications. An indirect method will be used to produce Lu-177 (neutron capture followed by decay). Separation of the Lu-177 from the target material will enable us to provide carrier-free Lu-177 suita ...

DESCRIPTION (provided by applicant): Osteoporosis is a major and growing health care problem that responds inadequately to standard pharmacologic therapy. Because of its low bone mineral density, osteoporotic bone is mechanically weak and fractures more easily than normal bone. Moreover, fracture repair is compromised in osteoporotic patients. The work described in this Phase I STTR proposal aims ...

DESCRIPTION: (Adapted from Applicant's Abstract) Malaria is a disease which affects more than 300 million people each year and is fatal for 1.5 million. The overall objective of this STTR Phase I project is to produce a cGMP malaria vaccine consisting of the 42 kDa C-terminal polypeptide of P. falciparum merozoite surface protein-1 (MSP1.42) to be formulated with ...

DESCRIPTION: (Adapted from the Applicant's Abstract) Traumatic spinal cord injury (SCI) leads to permanent loss of motor function and control of function below the level of the injury. A significant portion of the loss is due to secondary factors rather than the initial trauma. These factors include increased extracellular concentrations of glutamate which ha ...

DESCRIPTION (provided by applicant): Cocaine abuse remains a grave concern for the American, and increasingly the world, population. As no current therapeutic agents are available to assist cocaine addicts in achieving and maintaining abstinence it is important that new pharmacotherapies be developed. One important question not usually addressed in the development ...

DESCRIPTION (provided by applicant): Up to 3 percent of populations worldwide have psoriasis. A large number of the patients with psoriasis can be treated using UV light exposure. We propose to employ a light modulating microchip based on recent Micro Electro Mechanical Systems (MEMS) technological developments to build an Automated Psoriasis Treatment System. The overall goal of Phase I a ...

DESCRIPTION (adapted from applicant's abstract): The long-term goal of this project is to develop a rapid, safe, and sensitive test for the abnormal isofomms of prion (PrP/res) proteins associated with the transmissible spongifomm encephalopathies (TSE). The Surface Enhanced Raman Immunoassay (SERIA) assay to be evaluated will facilitate testing of sample ...