Award Data

Obesity and its associated metabolic complications including diabetes are becoming increasingly prevalent in the general population as well as in military personnel. Brown adipose tissue (BAT) is a major site of energy expenditure through thermogenesis, which is mediated by the mitochondrial uncoupling protein-1 (UCP1). Studies in animals over the last 30 years as well as recent data in humans str ...

Bioengineering offers an efficient and robust route for the production of enzymatic catalysts such as chloroperoxidase (CPO). The CPO from Caldariomyces fumago can catalyze non-specific halogenation of electrophilic organic molecules, epoxidation and hydroxylation of olefins and organic sulfides, and generation of free chlorine from chloride ion. The objectives are to: A. Develop a Caldari ...

The US Army has identified limitations of the DMFC (poor efficiency) and RMFC (complex system, high temperature process) approaches, and is soliciting innovation that will enable high efficiency hydrogen generation from methanol in a simple approach that has minimal thermal signature. It is the objective of this project to address these needs through the development of a novel hybrid electrochemic ...

In this collaborative STTR project between Vibratess LLC and UVA, we intent to conduct a combined theoretical and experimental study of plasmonic architectures for utilization with biological and chemical sensing in the THz spectral range. Plasmon Polariton (SSPP) devices that utilize metamaterials constructed of a conductor with sub-wavelength periodic structural features on it surface can tailor ...

Obtaining support from the local population is crucial for successful counterinsurgency (COIN) operations. US forces often fail to adequately understand the ethnographic characteristics of foreign populationswarfighters need access to ethnographic methods which help them to rapidly capture and interpret cultural, social, and economic data. A warfighter in high-risk areas needs easy-to-use tools th ...

Beginning from an advanced stage of development, this Phase I STTR project will produce designs and prototypes for a ricin-specific artificial antibody constructed using DNA origami. These novel constructs will provide both a capture function (mimicking the properties of an antibody) and intrinsic electro-optical reporting functionality, a significant improvement over current antibody capability. ...

The overall objective of this program is to enable low-cost production of high performance visible, IR and bispectral obscurants for improved ground force stealth and protection across the Armed Forces. In order to realize this goal, NanoSonic and Virginia Tech will build on promising Phase I results to investigate synthetic and processing approaches, optimize materials synthesis and processing, ...

In this effort, Physical Sciences Inc. will develop and implement algorithms and hardware to perform the fusion of information obtained from multiple LWIR passive hyperspectral sensors to provide the capability to determine the extent, absolute geo-location, and 3-D concentration distribution of chemical threat clouds from mobile platforms. The effort will be conducted in conjunction with Professo ...

This proposed project is concerned with the design, fabrication, and demonstration of a new class of plasmonic nanostructures for single molecule surface-enhanced Raman spectroscopy for biological and chemical sensing applications. A complete design of the plasmonic nanostructures with large local field enhancements (E/E0>100) will be formulated, and the fabrication procedures will be developed fo ...

The amount of new malware encountered daily is accelerating at an unprecedented rate, an explosion that is also reflected in target and attack vector diversity. There has also been a dramatic increase in the use of malware kits, a problem in its own right because kits allow adversaries to easily create one-time-use malware variants for which generic signatures and general solutions are neither pra ...