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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Adaptive Daylighting Control System

    SBC: Orion Engineering Company            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Energy
  2. Aerosolized hyaluronic acid as a treatment for emphysema

    SBC: EXHALE THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic obstructive pulmonary disease afflicts 12-14 million people in the US and in an advanced form, emphysema, disables 2 million and ultimately leads to death. No approved, existing treatment can arrest emphysema's progressive destruction of the lung. Exhale Therapeutics, Inc intends to develop and commercialize aeros ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Cancer is America's second leading cause of death. Many approved cancer drugs, such as bortezomib (Velcade), are cytotoxic agents that kill normal cells as well as tumor cells. Therapeutic benefit depends on tumor cellsbeing more sensitive than normal cells, thereby allowing clinical responses to be achieved at relatively safe drug doses; however, damage t ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. A NEW METHOD FOR MONITORING SPECIFIC NEUROTRANSMITTERS

    SBC: CC Technology            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed research will develop two prototype analyzers, one of which will be interfaced with a perfusion probe for neurotransmitters, and their metabolites, Surface Enhanced Raman Assay (SERA) using Surface Enhanced Resonance Raman Scattering (SERRS). The first prototype will be placed in a translational researc ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  5. A NOVEL BIS-INDOLE COMPOUND AGAINST CATHETER COLONIZATION

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Infections associated with medical devices can be serious and even fatal. Catheter colonization and production of a biofilm on the surface of a catheter shortly after implantation are normally the prelude for infections. A number of antimicrobial-treated catheters have been developed to combat these infections, however, many of them have limited clinical effica ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. A P. falciparum MSP1 p42/QS-21 malaria vaccine

    SBC: Agenus Inc.            Topic: N/A

    DESCRIPTION: (Adapted from Applicant's Abstract) Malaria is a disease which affects more than 300 million people each year and is fatal for 1.5 million. The overall objective of this STTR Phase I project is to produce a cGMP malaria vaccine consisting of the 42 kDa C-terminal polypeptide of P. falciparum merozoite surface protein-1 (MSP1.42) to be formulated with ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  7. A Tunable Interferometric Random Optical Cross-Switch

    SBC: Scientific Solutions, Inc.            Topic: N/A

    A random access, solid-state, optical cross-switch capable of 770 channel discrimination in the telecommunications C-band is designed and proven as an alternative to current thin-film WDM devices and as a mechanically robust alternative tomicroelectromechanical (MEMS) WDM devices. The device may be used in multiplexing (mux), demultiplexing (demux), or complete cross-switch configurations, and is ...

    STTR Phase I 2001 Department of DefenseMissile Defense Agency
  8. BEHAVIORAL TECHNOLOGY FOR INSTRUCTIONAL READINESS

    SBC: PRAXIS, INC.            Topic: N/A

    This application seeks support for an STTR Phase I project to develop and study a computer software product for computer-managed evaluation and instruction with children who have severe mental retardation, autism, and other intellectual disabilities. The product is primarily targeted to those students who lack the behavioral prerequisites to participate in ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  9. Bottoms-Up In-Situ Vitrification of Hard-to-Treat Buried Mixed Wastes

    SBC: RESODYN CORPORATION            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Energy
  10. CARBOHYDRATE-BASED THERAPY FOR CRYPTOSPORIDIOSIS

    SBC: ULEX CORPORATION            Topic: N/A

    N/A

    STTR Phase I 1999 Department of Health and Human Services
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