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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Adaptive Management and Mitigation of Uncertainty in Fusion (AMMUF)

    SBC: Charles River Analytics, Inc.            Topic: MDA13T001

    Missile defense takes place in an uncertain and dynamic environment, so multi-sensor fusion must be employed to aggregate and merge disparate data from the battlefield. However, the fusion process is hindered by the vast amount of uncertainty in operational contexts, such as imprecise measurements and varying environmental conditions. Various algorithms and fusion processes have been developed to ...

    STTR Phase I 2014 Department of DefenseMissile Defense Agency
  2. Uncertainty Characterization Using Copulas (UC)2

    SBC: Boston Fusion Corp.            Topic: MDA13T001

    Boston Fusion, together with our teammate Syracuse University, propose a program of research and development, namely Uncertainty Characterization Using Copulas, which will lead to a parametric framework based on the statistical theory of copulas for modeling uncertainties in a centralized fusion architecture for the problem of target classification for ballistic missile defense applications. This ...

    STTR Phase I 2014 Department of DefenseMissile Defense Agency
  3. Micro-Particle Debris Characterization from Hyper-Velocity Impacts

    SBC: Bodkin Design & Engineering, LLC            Topic: MDA13T002

    An ultra-high speed visible and near-infrared (VNIR) hyperspectral radiometric temperature imager will be developed in this program. The instrument is based on a high speed hyperspectral imager spanning the wavelength range 0.4-0.9 micron and providing hyperspectral data-cubes at rates of 13,500 Hz or faster. The high speed spatial imagery provides trajectory information to determine size and spe ...

    STTR Phase I 2014 Department of DefenseMissile Defense Agency
  4. Intelligent Simulation Techniques for a Realistic, Unified Command and Control Training System (INSTRUCTS) for Missile Defense

    SBC: Charles River Analytics, Inc.            Topic: MDA13T005

    Given a specific window of opportunity for an incoming threat, the central Command, Control, Battle Management, and Communications (C2BMC) operator must dynamically manage the battle to achieve global and regional mission objectives. Seconds matter in these situations, and the C2BMC operator must be well versed in all potential scenarios, so that his actions are both quick and decisive. Currently, ...

    STTR Phase I 2014 Department of DefenseMissile Defense Agency
  5. Phased Array Beam Steering for High Power Lasers

    SBC: Triton Systems, Inc.            Topic: MDA13T008

    To enable new directed energy systems which are much lighter, smaller and more efficient, new types of optical phased array beam steering are required. In this Phase I STTR, Triton Systems teamed with our academic partner, will demonstrate a new family of reflective phase modulation elements based on recent advances with a new electro-optic material which has been shown to add dynamic tunability ...

    STTR Phase I 2014 Department of DefenseMissile Defense Agency
  6. Modeling Operator Reasoning and Performance for Human-in-Control Simulation (MORPHIC)

    SBC: Charles River Analytics, Inc.            Topic: MDA12T006

    Propose development of a human-in-control (HIC) modeling capability that can: (1) represent the breadth of operator decision-making processes across missile defense elements, (2) scale to deliver the appropriate level of fidelity, and (3) be extensible to future operator needs. To provide this HIC modeling capability, we propose to develop and evaluate a full-scope prototype of Modeling Operato ...

    STTR Phase II 2014 Department of DefenseMissile Defense Agency
  7. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD, LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Assessing the Bite Counter as a Tool for Food Intake Monitoring: Phase II

    SBC: BITE TECHNOLOGIES, LLC            Topic: 300

    DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Development of PAR2 Inhibitors for the Treatment of Nonalcoholic steatohepatitis

    SBC: OASIS PHARMACEUTICALS, LLC            Topic: NIDDK

    DESCRIPTION provided by applicant Non alcoholic steatohepatitis NASH is characterized by fatty changes in the liver with inflammation and hepatocellular injury that in advanced stages leads to fibrosis and cirrhosis and high mortality rates NASH is frequently associated with other common metabolic abnormalities such as insulin resistance and visceral obesity Liver transplantation is curren ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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