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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  2. Developing a robust and scalable calibration approach to low-cost AQ sensing

    SBC: Aerodyne Research, Inc.            Topic: 813

    Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring widespread at an affordable price. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack of understandi ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  3. Development of a Rapid Monitoring System for Detection of Pathogens in Marine Aquaculture

    SBC: InnovaPrep, LLC            Topic: 836

    pathogens in marine aquaculture waters. Phase II research will look to improve sample concentration, cell lysis, and DNA purification techniques that were developed in Phase I. More specifically, optimization of the prototype lysis/elution fluid will be further developed for cell lysis using BSL-1 organisms, Vibrio harveyi, a surrogate for pathogenic Vibrio ssp. Techniques will be developed to ove ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  4. OpenORB Low-Cost Mooring Location Beacon for Costal Applications

    SBC: Triton Systems, Inc.            Topic: 825

    Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with minimal time and effort. ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  5. Phase II Commercialization of HABStats: A Harmful Algal Bloom Species, Toxin and Total Phytoplankton Identification System

    SBC: CoastalOceanVision, Inc            Topic: 821

    In Phase I, we developed a prototype instrument for counting, sizing and identifying both non-toxic and toxic Harmful Algal Bloom (HAB) species. We did this by integrating three innovative technologies: High-throughput color, Light Field Imaging Flow Cytometry to acquire morphological information for each cell, Raman spectroscopy to acquire species-specific molecular information on pigments and tr ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  6. Automated peak fitting and analysis software for advanced gas chromatography and mass spectrometer systems

    SBC: Aerodyne Research, Inc.            Topic: 827

    TECHNICAL ABSTRACT: Recent advances in gas chromatographic (GC) and mass spectrometric (MS) techniques for atmospheric measurements have led to highly complex data sets that have overwhelmed the capabilities of current data analysis software. We propose a new method for the automated reduction of chromatographic data using peak-fitting algorithms. By relying upon constrained peak-fit parameterizat ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Development of a Portable 3-dimensional Variational (3DVAR) Data Assimilation Module for NOAA Operational Forecasting Systems

    SBC: REMOTE SENSING SOLUTIONS, INC.            Topic: 814

    TECHNICAL ABSTRACT: We propose to continue the development of a generalized 3DVAR data assimilation module, in an open-source and non-proprietary programming language, which is compatible with FVCOM and incorporated into the Lake Erie Operational Forecast System (LEOFS). We will leverage our experience and expertise in using 3DVAR for a ROMS-based real-time forecast system for the California coast ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Automated HCl laser monitor for long term and flight deployments

    SBC: Aerodyne Research, Inc.            Topic: 813

    TECHNICAL ABSTRACT: Tropospheric oxidation capacity is dominated by HOx photochemistry, however halogen atoms and oxides significantly affect these chemical cycles. A sensitive and robust measurement of gaseous HCl is critically important to improve our understanding of halogen chemistry and its impacts on the spatial and temporal oxidation capacity of the atmosphere. In Phase I, we met all of our ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Absolute Distance Interferometer for Manufacturing Metrology Applications

    SBC: Bridger Photonics, Inc.            Topic: NA

    Bridger Photonics, Inc. proposes to develop an absolute length metrology sensor that will simultaneously provide >1,000 measurements per second, 0.5 m maximum measurement distance. Bridger’s solution is will fill a gap in precision measurement technology for applications that require rapid monitoring of macroscopic distances such as positioning and calibration of surface metrology systems (CMM, ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  10. High-Throughput Single-Nanoparticle Magnetic Analysis Platform Using Diamond Magnetic Imaging

    SBC: Quantum Diamond Technologies Inc            Topic: NA

    Magnetic nanoparticles are widely-used tools over a range of industries, but have particularly powerful biomedical applications for clinical and research diagnostics, clinical therapy, and basic life science research. Many of these applications require consistent sources for magnetic nanoparticles with narrow distributions of magnetic properties, but no technology is now commercially available for ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology

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