Award Data

With expanded connectivity, the spectrum of devices that are susceptible to cyber-attack is constantly increasing.Beyond this, given the increased processing power and capabilities of everyday IoT/embedded devices, cyber-attacks that previously only targeted endpoints (e.g., botnets, ransomware, DoS, DDoS, etc.) are now broadly applicable.Unfortunately, current cyber-threat detection solutions are ...

Air cargo security is critical to minimizing the overall risk to national security. However, screening air cargo with current state-of-the-art computed tomography (CT) imaging is a complex and challenging task for screeners. To address current complexities and challenges, Charles River Analytics proposes to design and demonstrate Supportive Intelligence and Fusion Technology to Ecologically Repres ...

Physical Sciences Inc. (PSI) proposes to develop an air cargo screening software suite that automatically parses air cargo waybills and detects and localizes the reported cargo contents within X-ray images obtained during screening. The software will utilize state-of-the-art machine-learning (ML) and natural language processing techniques to rapidly analyze and correlate manifests with associated ...

The Synthetik team is pleased to provide this Phase I SBIR proposal to develop a distributed, interoperable, ISO 18013-5-compliant and mdoc-based digital software badge (DSB). The DSB will provide the capability to prove a first responder personnel’s identity and qualifications onsite securely and efficiently in a disaster response operating environment.During Phase I we will demonstrate th ...

To achieve the goals for the DHS SBIR topic “MCX Server-to-Server Communication, voice communications, 3GPP-Standards” (DHS231-005) to develop a unified process, strategy, and methodology to achieving interoperability of MCX server-to-server communications and to create a test tool for conformance and interoperability testing for MCX server-to-server communications, we will develop the ...

Project Summary Surgery and acute post-operative pain are major contributors to persistent pain, chronic pain, and opioid dependence. Currently, there are no products on the market in the United States that can be used to monitor surgical nociception. Existing products use indicators that are susceptible to intraoperative influences such as blood loss, anesthetic drugs and antihypertensives. This ...

Project Summary / Abstract Nerve injuries arising from trauma, disease, or as a surgical necessity, lead most often to permanent loss of some or all functions mediated by the injured nerves. 50,000 peripheral nerve procedures are performed every year in the US, and 300,000 across Europe. After complete transection of a nerve, the optimal clinical procedure for nerve repair remains the surgical end ...

Despite prevalent use of anti-platelet and anti-lipid therapies, stroke remains the third major cause of death and is the leading cause of adult disability in the US with an estimated cost in the range of $34 billion annually. Approximately 20% of the annual 795,000 stroke patients die within one year and 15-30% are permanently disabled. Antiplatelet therapy is mainly used for primary prevention o ...

Lupus nephritis (LN), an immune complex-mediated glomerulonephritis, affects up to two-thirds of patients with systemic lupus erythematosus. Despite standard treatment protocols, progression of the most aggressive forms of LN (class III and IV) to end-stage renal failure remains high. Thus, there is a need for biomarkers of therapeutic response that would allow physicians to make better-informed t ...

Project Summary: Alcoholic Cardiomyopathy (ACM) is the most prevalent form of ethanol-induced heart damage. Alcohol dose-dependently induces ACM, characterized by progressive reduction in myocardial contractility and ventricular dilatation, culminating in heart failure. At the cellular level, chronic alcohol consumption results in cardiomyocyte death, cardiac inflammation, and cardiac fibrosis. Th ...