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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Self-Sustaining Crop Production Unit
SBC: FREIGHT FARMS, INC. Topic: T604NASA's goals to explore deep space through manned missions requires development of self-sustaining life support systems. A diverse team from Freight Farms, Inc. have partnered with Clemson University to merge knowledge of sustainable farming with engineering expertise to create off-grid infrastructure for self-sustaining plant life that will assist NASA with their goals. Freight Farms' current pro ...
STTR Phase I 2016 National Aeronautics and Space Administration -
Antibody targeting of ADAM for treatment of triple negative breast cancer
SBC: ADECTO PHARMACEUTICALS, INC. Topic: NCIDESCRIPTION provided by applicant Triple negative breast cancers TNBCs account for of breast cancer deaths and lack targeted therapies Drs Sonenshein Mineva and Romagnoli and their co workers recently identified the non essential cell surface protein ADAM A Disintegrin and Metalloprotease as a pivotal promoter of breast tumor growth and metastasis and validated it as a target o ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Novel Dental Adhesives to Prevent Recurrent Caries
SBC: CuRE Innovations, LLC Topic: NIDCRDESCRIPTION provided by applicant Bacterial related marginal decay is the top reason for failure and retreatment of resin based composite restorations RBCs Retreatment of these restorations costs both the patients and insurance companies billions of dollars per year The weak point of the system is the zone known as the hybrid layer where the adhesive bonds the RBC to the dentin There are ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Nanoparticle Delivery System for Ewing Sarcoma Treatment
SBC: NANOVALENT PHARMACEUTICALS INC Topic: 102DESCRIPTION provided by applicant This Phase I STTR project seeks to demonstrate proof of principle that novel targetable nanoparticles can delivery therapeutic substances to human tumor cells and reduce tumor burden in metastatic cancer The concept for these nanoparticles is based on the polymerized liposome nanoparticle PLN that displays functional antibodies that target tumor cell surfac ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Lipidated Stable BAM8-22 Offers a Promising Therapeutic for Neuropathic Pain
SBC: On Target Therapeutics, LLC Topic: 106DESCRIPTION provided by applicant Neuropathic pain is a serious health problem that affects millions of people worldwide and occurs in as much as of the general population The management of neuropathic pain in patients is complex with an estimated of individuals refractory to existing analgesic therapies The aging population the diabetes epidemic and the significant cohorts of can ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Novel mechanism for the treatment of epilepsy: New Vitamin K analogs target energetics and have low toxicity due to excellent specificity and low dose requirements compared to current therapies
SBC: NEUROENE THERAPEUTICS INC Topic: 106DESCRIPTION provided by applicant Epilepsy is the th most common neurological disorder with in people developing epilepsy the occurrence of more than one unprovoked seizure at some point in their lifetime Unfortunately of all patients have intractable medication resistant epilepsy Thus new anti epileptic drugs AEDs that target alternative mechanisms of action are needed ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Targeted Polymerized Shell Microbubbles to Image Surgical Adhesions
SBC: NANOVALENT PHARMACEUTICALS INC Topic: NIGMSDESCRIPTION provided by applicant The long term goal of this Phase I STTR project is to develop a commercially viable ultrasound contrast reagent UCR that will allow the noninvasive identification of newly forming abdominal adhesions after surgery Successful implementation would have significant impact because we would remove the impediment to clinical testing of anti adhesion therapies and ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Non-Invasive, Highly Specific Detection of Oxytocin in Biological Fluids
SBC: GINER INC Topic: NICHDDESCRIPTION provided by applicant Non Invasive Highly Specific Detection of Oxytocin in Biological Fluids Oxytocin a neuropeptide hormone plays an important role in a variety of complex social behaviors including affiliation sexual behavior and aggression It is best known for its role to facilitate the birth process through induction of myometrial muscle contractions However recent studi ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Developing Therapeutics That Target RAD To Treat Leukemia and Lymphoma
SBC: Cyteir Therapeutics, Inc. Topic: NCIDESCRIPTION provided by applicant Genomic instability is a hallmark of cancer and represents a targetable vulnerability yet is underdeveloped as a therapeutic area The central goal of this Phase program is to complete the early preclinical development of a new class of new cancer therapeutics that uniquely target RAD delivering effective cancer cell selective therapy in subsets of bioma ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Inhibitors of the viral nucleoprotein polymerase co factor interaction for human RSV and MPV therapy
SBC: MICROBIOTIX, INC. Topic: NIAIDHuman respiratory syncytial virus hRSV and human metapneumovirus hMPV are non segmented negative strand viruses NNSV and are the leading causes of acute respiratory tract infections in infants worldwide In addition hRSV is a significant cause of disease in elderly populations and can often be fatal for patients with compromised immune systems Currently no vaccines are available and exis ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health