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CYSTIC FIBROSIS (CF) IS A LETHAL GENETIC DISEASE AFFECTING THE WHITE POPULATION IN THE UNITED STATES AND EUROPE. THE GOAL OF THIS PROJECT IS TO USE RECOMBINANT DNA TECHNOLOGY TO GAIN THE INFORMATION NECESSARY TO DESIGN A TEST FOR CF GENE CARRIERS. IN THIS PROJECT LYMPHOBLASTOID CELL LINES WILL BE ESTABLISHES FROM MEMBERS OF LARGE CF PEDIGREES TO PROVIDE A SOURCE OF DNA FROM FAMILY MEMBERS. LATER, ...

OPTICAL COMPUTERS ARE RECOGNIZED AS POTENTIALLY USEFUL ELEMENTS IN THEQUEST TO MEET THE INTENSE BATTLE MANAGEMENT COMPUTATIONAL REQUIREMENTSOF STRATEGIC DEFENSE. CURRENTLY, OPTICAL COMPUTERS ARE GREATLY LIMITED IN PERFORMANCE BECAUSE NO EXISTING NONLINEAR LIGHT MODULATION DEVICE SIMULTANEOUSLY OFFERS FAST OPTICAL SWITCHING WITH THRESHOLD HIGH GAMMA, HIGH SPATIAL BANDWIDTH, LOW POWER DISSIPATION, O ...

DEVELOPMENT OF A SOFT INGNITION SYSTEM FOR SELF CONTAINED MUNITIONS IS PROPOSED. THE IGNITER WILL RELY ON A LASER\FIBER OPTIC SYSTEM TO ACHIEVE SIMULTAVEOUS MULTIPLE POINT IGNITION AT SEVERAL AXIAL LOCATIONS IN THE CENTER CORE PRIMER TUBE. PHASE I OF THE PROGRAM CONSISTS OF A PROOF-PRINCIPLE DEMONSTRATION OF THE CONCEPT THROUGH EXTENSIVE LABORATORY TEST LEADING TO AN IGNITER TUBE DESIGN WITH UNIFO ...

INVESTIGATE POTENTIAL OF A NOVEL CONCEPT TO GENERATE SPECIFIC WAVELENGTH REGIONS OF HIGH INTENSITY RADIATION AND/OR PLANAR BLAST WAVES TO PRODUCE, ON CLOSE-BY (TARGET) STRUCTURES AND/OR MATERIALS, THE THERMAL AND/OR SHOCK LOADINGS DELIVERED BY SINGLE PULSE OR REPETITIVE PULSE LASERS. THE CONCEPT, IF SUCCESSFUL, COULD APPLY OVER LARGE (ONE FOOT OR MORE) DIAMETER AREAS ON LARGE, SCALABLE STRUCTURES/ ...

RECHARGEABLE POWER SOURCES POSSESSING HIGH ENERGY DENSITIES, BRIEF BUTREPETITIVE HIGH CURRENT OUTPUTS, AND THOUSANDS OF DUTY CYCLES ARE REQUIRED FOR STRATEGIC DEFENSE SYSTEMS. TO ADDRESS THESE NEEDS, HIGH SURFACE AREA, THIN FILM CATHODES ARE BEING FABRICATED FOR AMBIENT TEMPERATURE LITHIUM BATTERIES. THESE CATHODES FEATURE AN ARRAY OF APPROXIMATELY L MICROMETER MICROCRYSTALLITE TIS2 PLATES ORIENTE ...

A NEED EXISTS TO DEVELOP A RELIABLE, COST EFFECTIVE POWER PLANT AND STORAGE SYSTEM FOR AN ELECTROMAGNETIC AIRCRAFT LAUNCHER. THIS SYSTEM CAN BEST BE DEVELOPED AROUND A HIGH ENERGY DENSITY FLYWHEEL COUPLED TO AN ADVANCED ELECTRIC GENERATOR. CONVENTIONAL POWER GENERATION CONCEPTS WOULD BE USED TO CHARGE THE FLYWHEEL BETWEEN LAUNCHES. THE CONTRACTOR WILL REVIEW THE CURRENT STATE-OF-THE-ART IN THE KEY ...

THE CURRENT PROCESS PRODUCES 100 MICRON NEEDLESHAPED PARTICLES OF NITROGUANIDINE WHICH ARE NOT SATISFACTORY FOR HIGH SOLIDS CONTENT FORMULATION; 400-600 MICRON SIZED SPHERICAL OR CUBICAL PARTICLES ARE DESIRED. EXPLORATORY DEVELOPMENT OF A NEW PROCESS USING SUPERCRITICALFLUIDS IS DESCRIBED. THE CONCEPT IS BASED UPON THE ABILITY OF A SUPERCRITICAL FLUID TO ACT AS A NUCLEATING MEDIUM OR TO DISSOLVE I ...

A PROGRAM IS PROPOSED TO EVALUATE THE FEASIBILITY OF DEVELOPING A FORTY-POUND COMPACT LIDAR SYSTEM BASED ON A UNIQUE LSI LASER DESIGN. THE GOAL IS A SYSTEM HAVING FOUR FREQUENCY AGILE COAXIALLY ALIGNED CO2 LASER BEAMS WITH AN ENERGY OUTPUT OF AT LEAST 100 MJ, A PRF OF 100 HZ, AND TUNABILITY TO 66 LINES AT A TUNING RATE OF 100 HZ. THE SYSTEM SHOULD USE NINE INCH COLLECTING OPTICS, STATE-OF-THE-ART ...

TWO-PHASE FLOWS WILL BE EMPLOYED IN MANY OF THE POWER GENERATION AND THERMAL MANAGEMENT SYSTEMS CURRENTLY UNDER DEVELOPMENT OR PROPOSED FOR FUTURE APPLICATION IN SPACE. WHILE THE PHENOMENA OCCURRING IN TWO-PHASE FLOW HAVE BEEN STUDIED EXTENSIVELY FOR EARTH-BOUND SYSTEMS, RELATIVELY LITTLE IS KNOWN ABOUT THE EFFECTS OF MICROGRAVITY ON TWOPHASE FLOWS. AN ORGANIZED RESEARCH EFFORT IS NEEDED TO PERMIT ...

THE OBJECTIVE OF THE PROPOSED RESEARCH IS TO LIMIT VOLTAGE DELAY, ANODE CORROSION DURING INTERMITTENT USAGE AND TO INCREASE THE CURRENT CAPABILITY AND CAPACITY OF LI/SOCL(2) CELLS THROUGH THE USE OF NEW ELECTROLYTE SALTS. THE PRINCIPLES USED WILL BE THOSE WHICH HAVE SUCCEEDED IN THE PAST, NAMELY, BY LIMITING THE CONCENTRATION OF THE ELECTROLYTE SALT AND BY USING THE LITHIUM SALTS OF LARGE ANIONS W ...